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People who have always lost weight and have not reached their goals may often encounter this scenario - when eating sweet or high-calorie foods, they will always constantly hint to themselves: "After eating this bite, they will not eat", but they will send food into their mouths
On September 7, 2022, a team of Professor Charles Zuker from Columbia University published a research paper titled "Gut-Brain Circuits for Fat Preference" online in nature magazine, which found that fat entering the gut triggers a signal that travels along nerves to the brain, driving people's cravings for
Consumption of high-sugar, high-fat processed foods in both developed and developing countries has seen catastrophic growth
The researchers wondered whether fat needed to activate specific brain circuits that drove animal behavioral responses to fat.
Figure 1.
The researchers then found the communication line that transmits information to the cNST, the vagus nerve, the main nerve
Figure 2.
The researchers further demonstrated that fats play a role after ingestion through the gut-brain axis to drive preference for fats
Interestingly, the use of drugs blocks the activity
Taken together, the study reveals different cells and receptors that use the gut-brain axis as a basic conduit for the development of fat preferences, and more importantly, by understanding the biological mechanisms by which food hijacks the taste and gut-brain axis, we have the opportunity to intervene
Original link:
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The content is [iNature]
