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NICE recommends pembrolizumab as an adjuvant therapy for stage 3 melanoma

 Last Update: 2021-12-24
 Source: Internet
 Author: User

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NICE has issued guidelines recommending Merck/MSD's Keytruda (pembrolizumab) as a monotherapy for the adjuvant treatment of stage 3 melanoma in adult patients with completely removed lymph nodes

guide

Melanoma is the second most common cancer in men and the third most common cancer in women

diagnosis

In the past decade, the field of melanoma has made tremendous medical advances, and immunotherapy treatment has become an indispensable part of it

immunity

Before adjuvant therapy became an available option for some patients, the standard postoperative practice for melanoma was active surveillance, closely monitoring patients to check for cancer recurrence

According to the Phase III EORTC1325/KEYNOTE-054 trial on which the approval is based, more than three-quarters of these patients will not have cancer recurrence within one year after initial treatment

In the overall median follow-up of 42.

Fig.

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