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Newly identified a potential cause of severe COVID-19

 Last Update: 2021-10-11
 Source: Internet
 Author: User

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premature aging disease

response surface

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SARS-CoV-2 is the coronavirus that causes COVID-19

Researchers have found that infection of SARS-CoV-2 cells causes an increase in the level of a protein called CD47 on the cell surface

CD47 is a so-called "don't eat me" signal, which is sent to the defense system of the immune system to protect cells from destruction

It is well known that risk factors for severe COVID-19 such as old age and diabetes are associated with higher CD47 levels

These data indicate that high CD47 levels induced by aging and viruses prevent an effective immune response and increase disease-related tissue and organ damage, leading to severe COVID-19

As therapies for CD47 are under development, this discovery may lead to improved COVID-19 therapies

Professor Martin Michaelis from the University of Kent said: “This is so exciting

Professor Jindrich Cinatl of the Goethe University in Frankfurt said: "These additional insights into the disease process behind COVID-19 may help us design better therapies and recognize the importance of the breadth of ongoing research

Katie-May McLaughlin, Denisa Bojkova, Joshua D.

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