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Newly discovered prion therapeutic target

 Last Update: 2022-10-02
 Source: Internet
 Author: User

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Prion diseases, such as bovine spongiform encephalopathy ("mad cow disease"), are deadly neurodegenerative infectious diseases that affect humans and other mammals and there is currently no cure

Prions are altered (i.

Although a large number of experimental and theoretical studies have been conducted, the molecular mechanisms that regulate the physiological to pathological changes in prion structure from physiological to pathological have not been clear

Therefore, it is possible to highlight the structure of human prion proteins, which are intermediate products

Structural and dynamical determinants of a β-sheet-enriched intermediate involved in amyloid fibrillar assembly of human prion protein

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