New research results of Korean agricultural revitalization agency, safflower seed improves anti-cancer activity and reduces kidney damage

On September 14, the Korean agricultural revitalization agency reported that safflower seed, a medicinal crop, can be used as an adjuvant in the treatment of colorectal cancer Cisplatin, a traditional anticancer drug, has high anticancer activity, but its side effects of renal injury are also large, so its clinical use is limited It was found that safflower seed extract could not only reduce the side effects of cisplatin on renal injury, but also improve its anticancer activity It was found that the inhibition rate of 100 g and 200 g of safflower seed extract was 40% and 42% respectively, while the inhibition rate of anti-cancer drugs was 51% In addition, the inhibition rate of the two extracts was significantly increased, i.e the inhibition rate of cancer cells was 67% when 100 g of safflower seed extract was used, and 73% when 200 g of safflower seed extract was used In addition, the killing effect of anti-cancer drugs and safflower seed extract on colorectal cancer cells was also improved compared with that of anti-cancer drugs alone The killing effect of 100 g safflower seed extract was increased by 9% and that of 200 g safflower seed extract was increased by 20% The protective effect of safflower seed on renal injury induced by anticancer drugs was measured by creatinine level in blood The concentration of creatinine in blood increased by 38% when the anticancer drugs were given alone, while the concentration of creatinine decreased by 11% and 16% when the anticancer drugs and safflower seed extracts were used together compared with the anticancer drugs alone