New plant extracts may be effective against HIV infection

Recently, a report was published in the International Journal of natural In the Research Report on products, researchers from the University of Illinois and other institutions found that a plant used to treat arthritis and rheumatism in Southeast Asia may contain a potential anti HIV compound stronger than the drug zidovudine (AZT); in this paper, researchers screened more than 4500 plant extracts, and finally screened out the name It is a compound of patentiflorin a, which mainly comes from the cot of willow leaf, and can help effectively resist HIV Photo source: the research findings of University of Illinois at Chicago are the result of years of cooperation of several research institutions Through screening a number of natural products with application value to the health of the body, researchers finally found this new anti HIV compound At the same time, researchers hope that this compound can significantly improve the health of people in low-income countries Willow leaf juxtaposition usually comes from leaves, stems and plant roots, which were collected in Ju Fang National Park in Hanoi Researchers analyzed thousands of plant extracts to identify which one can effectively resist HIV, tuberculosis, malaria and cancer And eventually they locked in the compound patentiflorin A This compound can effectively inhibit the key enzymes required by HIV, which can help HIV insert the genetic code of the virus itself into the DNA of the host cell AZT, as the first anti HIV drug developed by researchers in 1987, is still an important drug for HIV treatment AZT can inhibit the reverse transcriptase of the virus After the research on human cells infected with HIV, the research is carried out The researchers found that patentiflorin a can significantly inhibit the reverse transcriptase of the virus Compared with zat, compound patentiflorin a can significantly inhibit the activity of viral reverse transcriptase, and it can play a good role in both the early stage of the virus entering macrophages and its presence in T cells of the immune system, said researcher Rong At the same time, the new compound can also effectively resist drug-resistant HIV strains, which may help researchers develop new HIV drugs in the future Of course, this compound may also be a new anti HIV agent, which can be added to the current anti HIV drug mix to effectively increase the inhibition of the virus and the prevention of AIDS At the end of the day, the researchers said they were able to A if the compound can be synthesized in the laboratory, it may not be necessary to build farms to raise corresponding plants (willow leaf juxtaposition bed), which can greatly reduce financial investment Of course, more importantly, the new compound shows outstanding potential and value in resisting HIV infection Later researchers will also elaborate through more in-depth research To clarify the mechanism of patentiflorin a against HIV.