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New nanomaterials can enhance the anti-coronavirus effect of dendritic cell vaccines |
Science and Technology Daily, Beijing, September 2 (Yu Qunfang, Guan Tong, reporter Zhang Qiang) The reporter learned from the Academy of Military Medicine on the 2nd that the research team led by researcher Zhan Linsheng of the Academy found that new nanomaterials can enhance the anti-coronavirus effect of dendritic vaccines
.
Relevant research results were published in the authoritative journal "Advanced Materials" in the field of international materials
Academy of Sciences
If T cells are the heroic fighters in the body against diseases, infections and tumor cells, dendritic cells are "scouts" and "correspondents" that help T cells find viruses, bacteria, tumor cells and other "bad molecules"
.
In view of the important role of dendritic cells in initiating the immune response, people have successfully established an in vitro induction culture platform for dendritic cells to carry out more efficient antigen loading and activation of dendritic cells in vitro, and obtain fully functional dendrites.
The study shows that graphene oxide, a two-dimensional nanosheet material, can greatly enhance the anti-coronavirus effect of dendritic cell vaccines by regulating the formation of "immune synapses" between dendritic cells and T cells
Focus on the new crown pneumonia epidemic