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New model of polycystic kidney disease

 Last Update: 2021-11-11
 Source: Internet
 Author: User

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healthy plate model

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The anatomy and organ functions of frogs are surprisingly similar to those of humans

Observe the disease process in real time

Using CRISPR/Cas9, a method of shutting down gene functions, scientists target genes that play a role in cystic kidney disease

Artificial intelligence analyzes data through light microscope

To analyze data from such a large number of animals, the team used a technique called light plate microscopy, which generates a three-dimensional reconstruction of the entire tadpole and all its organs

Analyzing the results of the frog model in this way provides new insights into the early course of polycystic kidney disease

Thomas Naert, Özgün Çiçek, Paulina Ogar, Max Bürgi, Nikko-Ideen Shaidani, Michael M.

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