New knowledge: promising new food raw materials CaHMB --- functions, status quo, regulations and applications

CaHMB
, full name β
-
hydroxy
-
β
-
calcium methybutyrate, is one of the common forms of supplementation for
HMB
(β
-
hydroxy
-
β
-
methybutyrate).
HMB
can be used to promote muscle growth, enhance immunity, enhance the body's nitrogen fixation capacity, maintain protein levels in the body, widely used. In particular, it reduces the damage to muscle tissue after exercise, repairs muscle fibers, increases the role of muscle strength, burns body fat, accelerates wound healing, inhibits inflammation, etc. has received more attention and application. Health Yunhui specially wrote and edited this article, introduced
CaHMB
at home and abroad applications and prospects for your reference.CaHMB
introduction and role CaHMB
, full name β
-
hydroxy
-
β
-
calcium methylbutyrate, is
HMB
(β
-
hydroxy
-
β
-
methybutyrate) one of the common forms of supplementation.
HMB
(β
-
hydroxyl
-
β
-
methylbutybutyricate) is widely found in citrus fruits, certain vegetables such as broccoli, legumes such as alfalfa, and certain fish products.HMB
an intermediate metabolite of the essential amino acid lionine in the human body, and the human body itself can produce a small amount
HMB
. Under a normal diet, the body produces about
300 to 400
mg per day, of which
90%
is derived from the breakdown and metabolism of limeine.HMB
can be used to promote muscle growth, enhance immunity, lower cholesterol and low-density lipoprotein (
LDL
) levels in the body to reduce the incidence of coronary heart disease and cardiovascular disease, but also enhance the body's nitrogen fixation capacity, maintain protein levels in the body, widely used. In particular, it reduces the damage to muscle tissue after exercise, repairs muscle fibers, increases the role of muscle strength, burns body fat, accelerates wound healing, inhibits inflammation, etc. has received more attention and application.for the effects of
HMB
on muscle decay syndrome in old age, studies have studied
HMB
supplementation for
24
healthy elderly
(20,
women,
4
men
)
bedridden
the improvement of muscle condition after 10d
, the results showed a significant decrease in lean body mass in the control group during bed-staying
(P-0.02)
, while the
HMB
supplement effectively inhibited the decrease in lean body mass
(P-0.02)
. For bedridden elderly people, the

HMB
, which was only
10d
, showed a significant decrease in muscle loss compared to the control group. Other studies have shown that adding
HMB
to
2
to
4
weeks of
HMB
to bed-fed gastric tubes can also slow muscle breakdown. The elderly are the main group of inability, semi-inability, their ability to exercise is greatly limited, which further aggravates muscle decay, thus speculating that
HMB
supplement can be used as an effective means to prevent muscle decay in bed or paralysed patients.same time,
HMB
has been shown clinically to have the effect of accelerating wound healing and inhibiting inflammation. Studies show that
CaHMB
has the effect of accelerating protein synthesis and slowing protein consumption,
CaHMB
and glutamine, arginine and other combined use, can improve the patient's negative nitrogen balance, trauma, surgery and other responses play a positive role.regulations and applications of
CaHMB CaHMB
was recognized by the U.S. Food and Drug Administration's
GRAS
in

1995 as a medically nutritious food and special diet. In
20
years,
CaHMB
has been widely used in dairy products, chocolate products, beverages, energy bars and other foods. Especially in the United States in the field of sports nutrition is widely used, a large number of commodities in circulation, especially by the need for high athletic ability of professional athletes, fitness people welcome.In Japan,
CaHMB
is a raw material that is allowed by law to be added to food, can be added to ordinary food, sports nutrition food, weight loss food, beauty food and other fields, it can also be used as functional ingredients in capsules, tablets, solid beverages and other dietary supplements. For manufacturers and pharmacies,
caHMB
one of the most popular health components on the Japanese market. The
Super Medalist®
punch, widely used in sports nutrition supplements such as japan's リト
AC
, is one of the many
CaHMB

The "star product" in the sports nutrition supplement, which is the core material, contains
500mg CaHMB
in each bag, which is a muscle health product for professional athletes, with the main "improving athletic performance and promoting post-exercise recovery" "Request, emphasizing the inhibition of muscle protein breakdown after high-intensity training, promote muscle protein synthesis, enhance athletic endurance and other effects), oral beauty products (such as
fracora
developed by
Flowage®
Beauty Oral Solutions series, each bottle added
CaHMB 24mg
), muscle, trauma recovery specialty medical products (e.g. Abbott (Japan) developed solid beverage
Abound®
adds
1.5g CaHMB
, which accelerates wound recovery for soup burners, diabetics, postoperative wound healers, muscle-draining tumor patients, etc.) and slimming products such as a
HMB DIET PROGRAM COFFEE
's weight-loss coffee, which adds a combination of
CaHMB
and
BCAA
, is specifically designed for women to help women lose fat while completing the plastic requirements).Super Medalist ®
HMB DIET DIET COFFEE Flowage®
Beauty Oral Liquid SeriesChina
CaHMB
Regulations and Product DevelopmentChina,

2011, the former Ministry of Health announced the approval of β
-
hydroxy
-
β
-
calcium methylbutyrate (
CaHMB
) as a new resource food, the use of sports nutrition food, special medical use formula food, the recommended amount of ≤
3
g
/
days. In
2017
, it was requested to extend the use of β
-
hydroxy
-
β
-
calcium methamphetamine to beverages, dairy and dairy products, cocoa products, chocolate and chocolate products, as well as confectionery, baked goods, and special dietary foods. And
17th

May
, the State Health and Planning Commission issued the "announcement on
10
new food raw materials, such as milk and wood fruit oil"
2017
In document No.
7
of
, calcium β
-
hydroxy
-
β
-
methylbutyrate was officially listed as a new food ingredient and expanded in use.
CaHMB
recommended consumption of no more than
3
per day. As a new food ingredient, these groups should not be consumed because the safety of infants, children, pregnant women and lactating women is not assessed.overseas markets, the Chinese market
caHMB
late development time, regulatory barriers have just been cleared. Data show that
2016
China's market demand for
CaHMB
raw materials is only
2,
tons, while
in 2017
reached about
20,
tons, it is expected that
2025
market demand will exceed
1000
tons. The Chinese market is gradually entering an aging society, sports and fitness awareness is undergoing profound changes, the reduction of traditional medical costs and the rise of rehabilitation treatment, coupled with women's demand for health plastic fat reduction has become a
HMB
market development of various driving forces, China's potential consumer groups are the Japanese market
15
times, and with the improvement of China's consumer health awareness, the gradual improvement of muscle health awareness,
the improvement
application regulations of CaHMB, health products developed with
CaHMB
component as the core component will usher in a good development trend. CaHMB
Product Development direction 01
Sports Nutrition Products Since the
HMB

was discovered in
1996
Brands such as
EAS
,
Matrix
,
GNC
, etc., have launched
HMB
-related products and achieved success in the market. compared with foreign markets,
HPB
enter the Chinese market late, product development applications are mature enough. At present, Combite, Yan Jian and other domestic brands have
HMB
and protein powder combined for the sports fitness crowd launched
HMB
muscle-boosting products. With the rapid growth in demand for sports nutrition products, more and more companies are
new formulations
the HMB product. , of course, policies and regulations
new market
for HMB products.
general rules on
nutritional foods issued at the end of 2015,
HMB
recommended ingredients. With the improvement of domestic consumers'
HMB
, its compound formulation with crea acid may become another new hot spot in the field of sports nutrition food development. 02
shaped slimming products in addition,
HMB
also has its own unique advantages in the field of fat loss. With
HMB
's new concept of "healthy lipid reduction, muscle fiber" being responded to by brands, companies may consider adding
HMB
to their existing formulations to breathe new life into their products. it is worth mentioning that
HMB
's development in weight loss
/
-shaped products has also benefited from the findings of
HMB
animal and human fat reduction experiments. Clinical trials have shown that taking
HMB
with the appropriate amount of exercise can effectively improve body composition, to achieve fat reduction, weight loss and shape effect. 03
Special Medical Dietary Foods also mentions the success of solid beverages
Abound®
and a range of products developed by Abbott Corporation of Japan for soup-burning patients, diabetics, postoperative wound healers, muscle-depleting tumor patients, etc. In