New generation of targeted drugs significantly reduce the risk of lung cancer
-
Last Update: 2016-03-01
-
Source: Internet
-
Author: User
Search more information of high quality chemicals, good prices and reliable suppliers, visit
www.echemi.com
Lung cancer is the leading cause of cancer death in the world in the past decade EGFR (epidermal growth factor receptor) is an important driving gene in the diagnosis and treatment of lung cancer About 30% of non-small cell lung cancer (NSCLC) have EGFR gene mutations At the first Asia Regional Conference of the European Society of oncology held in Singapore recently, the results of an international cooperative study named lux-lung 7 were released for the first time The study showed that the second representative of the targeted drug, alfatinib, a tyrosine kinase inhibitor of skin growth factor receptor, significantly reduced the risk of lung cancer by 27% compared with the first generation of gefitinib The risk of treatment failure decreased by 27% and showed better long-term benefits Afatinib can irreversibly bind to EGFR receptor, permanently shut down the signal transduction pathway that cancer cells rely on for survival, so that cancer cells can not grow and reproduce Lux-lung 7 study is a prospective, randomized and open clinical study involving 319 patients with advanced NSCLC with common EGFR mutations from 13 countries, more than half of whom are Asian patients.
This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only.
This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of
the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed
description of the concern or complaint, to
service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content
will be removed immediately.
