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New crown cough phlegm open "bromohexin", pay attention to these 6 points!

 Last Update: 2023-02-02
 Source: Internet
 Author: User

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On December 7, 2022, the Comprehensive Group of the Joint Prevention and Control Mechanism of the State Council issued the "Guidelines for Home Treatment of Persons with New Coronavirus Infection", accompanied by the "Reference Table of Common Drugs for Home Treatment of Patients with New Coronavirus Infection", which pointed out that if people in home treatment have symptoms of coughing up sputum, they can take brohexazin
orally.

What are the precautions for using Bromhexine? In order for everyone to be able to use bromohexaxin safely, let's learn the relevant knowledge together!

Pharmacological action

Bromhexine is a mucolytic drug with a certain efficacy and wide application, which directly acts on the bronchial glands and can release the lysosomes of mucus-secreting cells, thereby depolymerizing mucopolysaccharides in mucus and reducing the viscosity of mucus; It can also cause the respiratory tract to secrete small molecules of mucin with low viscosity, so that the sputum becomes thin and achieves the purpose of
expectorant.

Reasonably grasp the indications and usage and dosage

Bromhexine expectorant has a significant effect and is widely used clinically, and authoritative guidelines recommend it for symptomatic treatment of respiratory diseases with sputum [1].

Solution for injection: intramuscular or intravenous
.
4mg at a time, 8-12mg (2-3 sticks).

Use after dilution with glucose injection solution for intravenous injection[2].

Tablets: orally
.
Adults, 1-2 tablets (8 mg each) three times a day [3].

Pay attention to these 6 points when using medication

After the use of brohexine, side effects such as nausea, abdominal pain, stomach upset, and skin allergic reactions may occur, and may also cause temporary elevation of serum aminotransferases [4].
Bromhexine is irritating to the mucosa of the gastrointestinal tract, and patients with gastritis or gastric ulcer should be used
with caution.
Some manufacturers of bromohexine tablets contain lactose components, lactose intolerance, lactase deficiency patients should not use
.
If stomach upset occurs, Bromhexain can be taken
with food.
Those who are allergic to bromohexine are banned, and those who are allergic should be used with caution [5].
Caution should be
exercised in patients with asthma.

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References:

[1] Chinese Medical Association, Journal of Chinese Medical Association, Chinese Medical Association General Practice Branch, etc.
Guidelines for the primary diagnosis and treatment of cough (2018)[J].
Chinese Journal of General Practitioners,2019,18(3):207-219.
)

[2] Drug information: Bromhexine hydrochloride injection, Shanghai Xudong Haipu Pharmaceutical Co.
, Ltd.
, Sinopharm H31022703
.

[3] Drug information: Bromhexine hydrochloride tablets, Jilin Huinan Huifa Pharmaceutical Co.
, Ltd.
, Sinopharm H22020869
.

[4] Instructions for bromohexyl hydrochloride tablets.

[5] Chinese Medical Association, Journal of Chinese Medical Association, General Practice Branch of Chinese Medical Association, etc.
Guidelines for the primary diagnosis and treatment of cough (Practice Edition, 2018)[J].
Chinese Journal of General Practitioners,2019,18(3):220-227.
)

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