Neuroology: An acute symptomatic attack of cerebral vein thrombosis.

In a recent study published in Neuroology, an authoritative journal in the field of neurology, which looked at the characteristics, predictive factors, and outcomes of acute symptomatic seizures (ASS) in patients with cerebrovenous thrombosis (CVT), researchers investigated 1,281 consecutive CVT adult patients in 12 hospitals within the International CVT Alliance.
researchers defined ASS as any seizure between the onset of symptoms and 7 days after diagnosis of CVT, and classified ASS as PRE-diagnosis ASS and post-diagnosis ASS.
epilepsy persistent state (SE) was also analyzed separately.
researchers analyzed the predictors of ASS and the association between ASS and clinical outcomes (improved Rankin scale) using multivariable logistic regression.
441 (34%) of the 1,281 eligible patients had ASS.
THES baseline prediction indicator is cerebral hemorrhage (ICH), adjusted ratio of 4.1, 95% confidence interval (CI) is 3.0-5.5), cerebral edema/terrier without ICH Plugs (aOR 2.8, 95% CI 2.0-4.0), cortical vein thrombosis (aOR 2.1, 95% CI 1.5-2.9), anabolic sinus blood Embolism (aOR is 2.0, 95% CI is 1.5-2.6), lesions of lesions (aOR is 1.9, 95% CI is 1.4-2.6), cranial cobwebs Sub-membrane hemorrhage (aOR is 1.6, 95% CI is 1.1-2.5) and female-specific risk factors (aOR is 1.5, 95% CI is 1.1-2.1).
93 patients (7%) had ASS only after diagnosis, preferably through corttic venous thrombosis (positive/negative prediction of 22%/92%).
80 (6%) patients were accompanied by SE, which can be independently predicted by ICH, lesions of neurologic dysfunction and cerebral edema/infarction.
and SE were not related to patient outcomes.
that one-third of CVT patients develop ASS and are associated with brain lesions and thrombosis.
researchers found no association between ASS and patient outcomes.
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