 Home > Active Ingredient News > Study of Nervous System > Neuron: The Ju Huang research team at Shanghai Jiao Tong University reveals reward neural circuits for repeated nail-biting or skin behaviors

Neuron: The Ju Huang research team at Shanghai Jiao Tong University reveals reward neural circuits for repeated nail-biting or skin behaviors

 Last Update: 2022-09-21
 Source: Internet
 Author: User

Tags

parathyroid hormone

1 2 dimethylbenzene

Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

Click on the blue word to follow us

The habitual habit of repeatedly nibbling on nails and surrounding skin over a long period of time is called Body-Focused Repetitive Behaviors (BFRBs

MPL-SST can encode information about self-grooming behavior

Photoactivation or chemogenetics chronic activation of somatostatin (SST) neurons in the medial parapontine nucleus (MPL) region of the midbrain promotes self-grooming behavior in female and male mice, and activation of non-SSTergic neurons does not play this role

Figure 1: MPL-SST-enabled neurons regulate self-grooming behavior

MPL-SST can neuronal upper and lower brain regions

Retrograde tracing virus experiments have found that MPL is mainly received from the central amygdala (CeA), terminal bed nucleus (BNST), ventral lateral midbrain periosteal gray matter (vlPAG), hypothalamic paraventricular nucleus (PVN), hypothalamus (IC), and auditory cortex (Au).

Figure 2: MPL-SST can input neurons into brain regions

MPL-SST can encode reward information on neurons

Intracranial self-stimulation or conditioned location preference experiments have shown that light-activated MPL-SST neurons promote mice to stay on the side

Figure 3: MPL-SST can encode reward information for neurons

summary

This paper reveals the regulation of repetitive stereotyped self-grooming behaviors of MPL-STT neurons through multiple viral tracing and optogenetic techniques, which are mainly achieved by the CeA➟MPL-STT➟VTA dopamine neural circuit

【References】

https://doi.

The pictures in the article are from references

This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

Related Products

Sodium bromide airuike

CAS No.: 7647-15-6

Industrial Grade

$10/KG EXW

Brivaracetam357336-20-0

CAS No.: 357336-20-0

API Grade

$100/KG EXW

Quetiapine fumarate CAS 111974-72-2

CAS No.: 111974-72-2

Pharmaceutical Grade

$100/KG EXW

Hot Tags

united states jobs(223)

jobs united states(236)

1 year treasury(277)

1 year subscription(296)

single use technology(195)

announcements today(81)

ups united states(221)

united states logo(227)

80 20 company(94)

healthy food name(42)

Hot Articles

The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.