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Neurology: The risk of neurodevelopmental disorders and autism in children after ischemic stroke increases, and comprehensive screening is necessary!

 Last Update: 2022-04-24
 Source: Internet
 Author: User

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Ischemic stroke is a rare but serious disease with a high risk of neurological complications such as poor motor outcomes, epilepsy, and cognitive impairment

Autism is characterized by varying degrees of difficulty with social interaction and communication, along with restricted, repetitive, and stereotyped behaviors, interests, and activities

Several studies have found an association between epilepsy of different etiologies, particularly genetics and autism, leading to the hypothesis that the two disorders are partly based on an impaired balance between inhibition and excitation

Ischemic stroke and autism in children are difficult to study prospectively because of the low incidence, which justifies the use of national registries with prospectively collected national cohort data

In this cohort study, patients with ischemic stroke between 1969-2016, aged <18 years, alive 1 week after stroke, and without previous autism, were identified in the Swedish National Registry

Of the 1322 index individuals, 46 (3.

The increased risk of autism after childhood ischemic stroke, especially in individuals with epilepsy, cannot be explained by preterm birth or small for gestational age

Source: Sundelin H, Söderling J, Bang P, Bolk J.
Risk of Autism After Pediatric Ischemic Stroke: A Nationwide Cohort Study [published online ahead of print, 2022 Mar 21].
Neurology.
2022;10.
1212/WNL.
0000000000200253.
doi :10.
1212/WNL.
0000000000200253Leave

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