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    Home > Active Ingredient News > Study of Nervous System > Neurology: The relationship between CT-based hypoperfusion index and the expansion of ischemic focus in patients with medium and large vascular stroke

    Neurology: The relationship between CT-based hypoperfusion index and the expansion of ischemic focus in patients with medium and large vascular stroke

    • Last Update: 2021-11-01
    • Source: Internet
    • Author: User
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    When a cerebral artery is occluded, the area of ​​the brain that supplies blood is ischemic
    .


    If blood flow is not restored, the ischemic brain will transform into a permanent infarction (core) over time


    Stroke

    The low perfusion index (HI) is a tool for evaluating stroke progression using CT perfusion imaging
    .


    Reperfusion stroke tests usually use core volume relative to time to estimate core progression.


    Recently, researchers have provided evidence about the performance of HI and evaluated the low perfusion index (HI) to compare patients with medium vessel occlusion (Mevo) and patients with large vessel occlusion (LVO) for a longer period of time since the onset of stroke The core progress rate


     

    The researchers evaluated the progression of infarction in 106 patients with acute stroke and CT perfusion
    .


    According to the core time standard of the reperfusion test, the core of rapid progressing patients is more than 70 mL within 6 hours after the start of stroke, and the core of slow progressing patients is less than 70 ml within 6 to 24 hours, mismatch ≥ 15 ml, and mismatch ≥ 1.


    • Among 106 patients with acute stroke, 6.
      6% were progressing rapidly, 27.
      4% were slow progressing, and 66% of patients were not classified as fast progressing or slow progressing according to the core time standard of the reperfusion test
      .
    • HI>0.
      5 means fast progress, which can distinguish fast progress from slow progress (AUC=0.
      94; 95%CI=0.
      80~0.
      99)
      .


      In 26 patients with MEVO, the core progression when HI>0.


       Literature source: https://n.


       https://n.


       

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