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Neurology: Relationship between cerebrovascular and Alzheimer's disease biomarkers and cholinergic leukogen degeneration in individuals without impaired cognitive function

 Last Update: 2022-09-30
 Source: Internet
 Author: User

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The degeneration of the cholinergic system during aging may be associated
with a variety of pathological processes.

The study evaluated the pathological effects
of amyloid and tau by cerebrospinal fluid Aβ42/40 ratio and phosphorylated tau protein (p-tau) levels.

Conclusion: In the elderly with normal cognitive function, white matter damage plays a central role
in the degradation of cholinergic pathways.

Source: Cedres N, Ferreira D, Nemy M, et al.

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