Neurology: Pregnancy hypertension and cognitive impairment

Researchers measured the cognitive abilities of 115 women with a history of HDP and 481 women with normal blood pressure in a recent study published in Neurology, an authoritative journal in the field of neurology, aimed at clarifying the link between high blood pressure (HDP) during pregnancy and cognitive impairment after 15 years of pregnancy.
the study was a nested cohort study that assessed cognitive function through cognitive tests in the last fifteen years of pregnancy (an average of 14.7 years and 90 percent in the range of 13.9 to 16.1).
researchers measured subjects' cognitive performance in different cognitive areas: executive function, processing speed, language memory, motor function, and visual spatial ability.
overall cognitive factor (g-factor) comes from the main component analysis.
among women with HDP, there were 80 (69.6%) pregnant women with high gestational hypertension (GH) and 35 (30.4%) with pre-eclampsia.
women with HDP had a g-factor lower than normal blood pressure in pregnant women (the average difference was -0.22, with an average range of -2.06; 1.29]）。
HDP was negatively associated with 15-word learning test results: Instant Recall (-0.25, 95% CI is -0.44 to -0.06) and Delayed Recall (-0.30, 95% CI -0.50 to -0.10).
GH women performed much worse on the 15-word study test than pregnant women with normal blood pressure.
that 15 years after pregnancy, HDP history is associated with poor work memory and speech learning independence.
association is mainly mediated by GH women.
clinicians and women who have experienced HDP should be aware of this risk.