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Neurology: Perivascular space and risk of developing dementia - Framingham Heart Study

 Last Update: 2022-10-12
 Source: Internet
 Author: User

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Dementia is devastating to individuals and families and has reached epidemic proportions, with more than 5 million people affected in the United States and 43.

Figure 1: Cover art of the paper

Figure 2: Graph of the paper results

With this, Jose Rafael Romero of Boston University et al.

In models that adjusted for vascular risk factors and cardiovascular disease, the risk of dementia steadily increased with the burden of PVS, with participants with class II PVS increasing by a factor of 2 (HR 2.

After adjusting for white matter high-density volume, covert infarction, and total brain volume, this association was still meaningful for the CSO, but not for BG

Similar findings have been made for AD, but vascular dementia is limited by the small number of events and is not statistically significant

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