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Neurology: Peking University Public Health Risk Prediction Model: Using the Chinese Kadoorie Biobank to Build and Predict the Risk of Ischemic and Hemorrhagic Stroke and Ischemic Heart Disease within 10 Years

 Last Update: 2022-05-25
 Source: Internet
 Author: User

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Cardiovascular disease (CVD), including ischemic heart disease (IHD), ischemic stroke (IS), and hemorrhagic stroke (HS), is the leading cause of the global disease burden

The first is to differentiate the risks between IS and HS

Based on the China Kadoorie Biobank (CKB), one of the largest population-based cohorts in the world, researchers have recently established practical disease-specific and overall cardiac outcomes based on widely available variables in Chinese RHR, including IHD, IS, and HS.

The researchers established gender models of ischemic heart disease (IHD), ischemic stroke (IS) and hemorrhagic stroke (HS), and total cardiovascular disease (CVD) in the Chinese Kadoorie Biobank

During the 11-year follow-up period, 489,596 people participated in the model study, including 45,947 IHD, 43,647 IS, and 11,168 HS patients

In addition to excluding blood lipids, this cardiovascular risk prediction model was also able to differentiate between IHD and stroke subtypes well

Classification of evidence: This study provides class I evidence that a predictive model incorporating accessible clinical variables predicts the 10-year risk of ischemic heart disease, ischemic stroke, and hemorrhagic stroke in a Chinese population aged 30-79 years

Source: Yang S, Han Y, Yu C, et al.
Development of Model to Predict 10-Year Risk of Ischemic and Hemorrhagic Stroke and Ischemic Heart Disease Using the China Kadoorie Biobank [published online ahead of print, 2022 Apr 11].
Neurology.
2022;10.
1212/WNL.
0000000000200139.
doi:10.
1212/WNL.
0000000000200139 Yang S, Han Y, Yu C, et al.
Development of Model to Predict 10-Year Risk of Ischemic and Hemorrhagic Stroke and Ischemic Heart Disease Using the China Kadoorie Biobank [published online ahead of print, 2022 Apr 11].
Neurology.
2022;10.
1212/WNL.
0000000000200139.
doi:10.
1212/WNL.
0000000000200139Leave

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