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Neurology: How does the sense of smell and cognitive motor risk relate

 Last Update: 2022-10-02
 Source: Internet
 Author: User

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Motor cognitive risk syndrome (MCR) is a pre-dementia syndrome characterized by subjective cognitive complaints and slow

Figure 1: Cover art of the paper

The olfactory function of the elderly is related to the gait speed, mobility and balance ability of the elderly, even if cognitive function

Figure 2: Graph of the paper results

The relationship between the performance of the Simple Olfactory Recognition Test (BSIT) and the risk of developing MCR was calculated using the Cox model and reported at the risk ratio (HR), with a 95% confidence interval (CI) adjusting

During the median follow-up of 3.

People with at-baseline olfactory loss (BSIT score ≤8) had an increased risk of MCR compared with people with normal olfactory function (26.

The comprehensive measurement of AD pathology and the presence of Lewy body pathology are inversely proportional to the BSIT score at the time of MCR diagnosis and are independently correlated (n=118).

The τ tangle density is a specific component of AD pathology, inversely proportional to olfactory function, and this correlation persists after controlling for mild cognitive impairment syndrome as well as the presence of Lewy body pathology

These results provide evidence that olfactory dysfunction precedes the occurrence of MCR and is associated with Alzheimer's pathology; Provides a clinical approach

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