Neurology: Coffee helps prevent Parkinson's.

2, 2020 /--- According to a new study published September 30, 2020 in the journal Neurology, even for people with a genetic mutation associated with Parkinson's disease, drinking coffee may reduce the risk of developing the disease.
"These results could help future research to explore caffeine-related therapies to reduce the risk of Parkinson's disease in people with associated genetic mutations," said study author Grace Crotty, M.D., of Massachusetts General Hospital in Boston and a member of the American Academy of Sciences.
", caffeine levels in the blood may also be used as biomarkers to help identify risk.
(Photo: www.pixabay.com) earlier studies have shown that coffee intake can prevent the development of Parkinson's disease in people without a genetic risk.
study looked at people with genetic mutations that increase the risk of Parkinson's disease.
the mutation is located in a gene rich in LRRK2 kinases rich in leucine, and the presence of abnormal gene mutations does not necessarily mean that people will necessarily develop the disease, so the researchers hope to identify other genetic or environmental factors that affect whether people develop the disease.
the study compared 188 people with Parkinson's disease with 180 without Parkinson's.
two groups included people with LRRK2 gene mutations and those without LRRK2 gene mutations.
researchers looked at the amount of caffeine in the blood, as well as the amount of other chemicals that caffeine produces when it is metabolized in the body, and the differences between groups.
people with the LRRK2 gene mutation had 76 percent lower levels of caffeine in their blood than those without Parkinson's.
people with Parkinson's disease with a normal copy of the gene had a 31 percent lower concentration of caffeine in their blood than non-carriers without Parkinson's.
caffeine intake was also lower in the diet of people with genetic mutations with Parkinson's disease.
with or without a genetic mutation, people with Parkinson's consume 41 percent less caffeine per day than those without Parkinson's.
we don't know if people prone to Parkinson's tend not to drink coffee, or if some people with mutations drink a lot of coffee and benefit from it," he said. (Bioon.com) Source: Even in people with Parkinson's gene, coffee may be protective Information Link: Association of caffeine and related analytes with resistance to Parkinson's disease among LRRK2 mutation carriers: A metabolomic study. First published September 30, 2020, DOI: