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A recent study published in the journal Neurology, an authoritative journal in the field of neurology, looked at the frequency, clinical and etiological characteristics, short-term and long-term outcomes of early recurrent transient cerebral ischemia (TIA).
this prospective observational cohort study included all TIA patients referred to an emergency department (ED) and diagnosed by angioneurologists.
rapid assessment and optimal secondary prevention were carried out within 24 hours.
the study's main endpoints were stroke and comprehensive outcomes, including stroke, acute coronary syndrome and vascular death at 3 or 12 months, with some patients being 60 months;
the researchers also assessed the consistency between TIA and subsequent stroke.
from August 2010 to December 2017, the study recruited a total of 1,035 patients (822 TIA, 213 TIA recurrences, or 21%). The relationship between
intracystic early warning syndrome and major atherosclerosis and early TIA recurrence is most closely related.
in each follow-up, the risk of early recurrent TIA sub-group stroke was higher, with most strokes occurring within 48 hours of TIA. tiain with lesions, diaphmo disorders and white matter softening in the early recurrence OF TIA subgroup,
, were independent predictors of stroke occurring in 3 and 12 months.
consistent with tiai and subsequent stroke etiology.
ABCD3 score predicted a higher risk of stroke recurrence throughout the follow-up period.
, the study is the first to assess the long-term outcomes of patients with early recurrent TIA.
observations of this study support the importance of timely detection and treatment of early recurrent TIAAs to reduce the early and long-term risk of adverse clinical outcomes.
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