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Neurology: Cardiovascular Risk Study in Finnish Youth: Persistently high levels of serum creatinine may be associated with better learning and memory function in middle-aged men!

 Last Update: 2022-05-23
 Source: Internet
 Author: User

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As the prevalence of dementia increases, effective means of enhancing cognitive health before cognitive deficits appear are critical

Serum creatinine is an indicator of renal function and can be used to calculate estimated glomerular filtration rate (EGFR)

The mechanism underlying the link between low serum creatinine and cognitive impairment is unclear

Using data from the Young Finns Cardiovascular Risk Study (YFS), researchers sought to investigate the longitudinal association between serum creatinine and cognitive performance in middle age

Participants in the Finnish Youth Cardiovascular Risk Study have been followed for up to 10 years since 2001

In men (N=973) and women (N=1,204), 4 serum creatinine trajectory groups were identified, all with clinically normal serum creatinine

The findings suggest that, in men, persistently high levels of serum creatinine may be associated with better memory and learning function in midlife compared with low levels of serum creatinine

Source: Hakala JO, Pahkala K, Juonala M, et al.
Repeatedly Measured Serum Creatinine and Cognitive Performance in Midlife: The Cardiovascular Risk in Young Finns Study [published online ahead of print, 2022 Apr 11].
Neurology.
2022;10.
1212/ WNL.
0000000000200268.
doi:10.
1212/WNL.
0000000000200268 Hakala JO, Pahkala K, Juonala M, et al.
Repeatedly Measured Serum Creatinine and Cognitive Performance in Midlife: The Cardiovascular Risk in Young Finns Study [published online ahead of print, 2022 Apr 11 ].
Neurology.
2022; 10.
1212/WNL.
0000000000200268.
doi: 10.
1212/WNL.
0000000000200268

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