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Lewy body disease is characterized by Lewy bodies composed of α-synuclein, and it encompasses a range of diagnoses , including Parkinson's disease (PD) and dementia with Lewy bodies (DLB)
Diagnostics (123) (123)
Several studies have evaluated (123) the diagnostic accuracy of I-MIBG myocardial imaging for LBDS
(123) (123)
The diagnostic accuracy of (123) I-MIBG myocardial scintigraphy in differentiating LBD from similar disorders has been determined based on large autopsy cases
The diagnostic accuracy of (123) I-MIBG myocardial scintigraphy in differentiating LBD from similar disorders has been determined based on large autopsy cases
This retrospective cross-sectional study included serial autopsy patients from the Aging Research Brain Bank who underwent 123I-MIBG cardionuclide scans
(123) Immunization (123)
- The data of 56 patients were analyzed, of which 30 were pathologically confirmed LBDS, and 26 had no pathological changes of LBD
This clinicopathological validation study demonstrated that (123) I-MIBG myocardial imaging can effectively differentiate LBDS from similar disorders
Source: Matsubara T, Kameyama M, Tanaka N, et al.
Autopsy Validation of the Diagnostic Accuracy of 123I-Metaiodobenzylguanidine Myocardial Scintigraphy for Lewy Body Disease.
Neurology.
2022;98(16):e1648-e1659.
doi:10.
1212/WNL .
0000000000200110 Matsubara T, Kameyama M, Tanaka N, et al.
Autopsy Validation of the Diagnostic Accuracy of 123I-Metaiodobenzylguanidine Myocardial Scintigraphy for Lewy Body Disease.
Neurology.
2022;98(16):e1648-e1659.
doi:10.
1212/WNL.
0000000000200110
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