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    Home > Active Ingredient News > Study of Nervous System > Neurology: Autopsy validation of the diagnostic accuracy of (123) I-m-iodophenylguanidine myocardial imaging for Lewy body disease

    Neurology: Autopsy validation of the diagnostic accuracy of (123) I-m-iodophenylguanidine myocardial imaging for Lewy body disease

    • Last Update: 2022-05-26
    • Source: Internet
    • Author: User
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    Lewy body disease is characterized by Lewy bodies composed of α-synuclein, and it encompasses a range of diagnoses , including Parkinson's disease (PD) and dementia with Lewy bodies (DLB)


    Diagnostics (123) (123)

    Several studies have evaluated (123) the diagnostic accuracy of I-MIBG myocardial imaging for LBDS


    (123) (123)

    The diagnostic accuracy of (123) I-MIBG myocardial scintigraphy in differentiating LBD from similar disorders has been determined based on large autopsy cases


    The diagnostic accuracy of (123) I-MIBG myocardial scintigraphy in differentiating LBD from similar disorders has been determined based on large autopsy cases


    This retrospective cross-sectional study included serial autopsy patients from the Aging Research Brain Bank who underwent 123I-MIBG cardionuclide scans


    (123) Immunization (123)

    • The data of 56 patients were analyzed, of which 30 were pathologically confirmed LBDS, and 26 had no pathological changes of LBD


      This clinicopathological validation study demonstrated that (123) I-MIBG myocardial imaging can effectively differentiate LBDS from similar disorders


      Source: Matsubara T, Kameyama M, Tanaka N, et al.
      Autopsy Validation of the Diagnostic Accuracy of 123I-Metaiodobenzylguanidine Myocardial Scintigraphy for Lewy Body Disease.
      Neurology.
      2022;98(16):e1648-e1659.
      doi:10.
      1212/WNL .
      0000000000200110 Matsubara T, Kameyama M, Tanaka N, et al.
      Autopsy Validation of the Diagnostic Accuracy of 123I-Metaiodobenzylguanidine Myocardial Scintigraphy for Lewy Body Disease.
      Neurology.
      2022;98(16):e1648-e1659.
      doi:10.
      1212/WNL.
      0000000000200110

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