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Neurology: Associations between trajectories of cardiovascular risk and events of cognitive decline and dementia

 Last Update: 2022-05-23
 Source: Internet
 Author: User

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The relationship between cardiovascular risk factors and cognitive decline and dementia has recently been demonstrated, however most studies have assessed this relationship through cross-sectional data, lacking knowledge of the longitudinal dynamics of this risk

Blood vessel

In a study published today in Neurology, the leading journal in the field of neurology, researchers aimed to test the hypothesis that accelerated, long-term accumulation of cardiovascular risk, as determined by the Framingham Risk Score (FRS), would Vascular risk was less favorable for cognitive and dementia status outcomes

The researchers evaluated a sample of initially healthy community residents recruited from a prospective cohort study

Among the 1,244 participants, 60% of the sample had an appropriate increase in cardiovascular risk over time, and the researchers observed a rapid increase in risk in 18% of participants and minimal changes in 22%

Alzheimer's disease dementia risk in carriers

CONCLUSIONS: The current findings suggest that longitudinal, cumulative trajectories of cardiovascular risk predict dementia risk and are associated with memory decline

Original source:

Bryn Farnsworth von Cederwald, et al.

Bryn Farnsworth von Cederwald, et al.
Association of Cardiovascular Risk Trajectory With Cognitive Decline and Incident Dementia .
Neurology.
2022.
https://n.
neurology.
org/content/early/2022/04/20/WNL.
0000000000200255 Association of Cardiovascular Risk Trajectory With Cognitive Decline and Incident Dementia

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