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Neurology: Application of MRI metabolomics in idiopathic intracranial hypertension to identify markers of disease and headache

 Last Update: 2022-10-02
 Source: Internet
 Author: User

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Idiopathic intracranial hypertension (IIH) is characterized by elevated intracranial pressure (ICP), leading to the risk of papilledema and permanent vision loss, in addition to chronic headaches, which greatly reduce quality of

Figure 1: Cover art of the paper

In addition, omentum and subcutaneous IIH fats exhibit unique site-specific lipogenic characteristics, with adipose tissue transcription to increase calorie storage

Defining the etiology of IIH and identifying biomarkers to guide diagnosis are considered to be top priorities for research, conducted

In this regard, Olivia Grech of the University of Birmingham in the United Kingdom believes that the investigation of the metabolic pathways involved in IIH may reveal the pathogenesis of the disease and make sense

They found: IIH had lower urea (CSF; The median of the control group±IQR 0.

Compared with the control group, the ratio of lactic acid: pyruvate increased (CSF; Control group 49.

Figure 2: Graph of the paper results

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