Neurology: A recurrent attack of cerebral vein thrombosis.

In a recent study published in Neuroology, an authoritative journal in the field of neurology, researchers investigated the registration centers of 1,127 CVT patients to assess the occurrence, characteristics, treatment, and predictive factors of late onset (LS) after cerebrovenous thrombosis (CVT).
researchers included adult patients from 12 hospital-based CVT registries who had a history of epilepsy or had follow-up for less than eight days.
researchers defined LS as a seizure that occurred seven days after diagnosis of CVT onset and used multivariable Cox regression to determine the predictor of LS.
researchers included 1,127 CVT patients, 123 patients (11%) experienced one or more LS (30 first LS per 1,000 people per year for the first time during a two-year mid-range follow-up period (1.0-6.3 for the IQR).
time for the first LS is 5 months (IQR is 1-16).
LS baseline predictive indicators include acute epilepsy (risk ratio of 7.0, 95% CI of 3.9-12.6), acute seizures without epilepsy (HR is 4.1, 95% CI is 2.5-6.5), cerebral hemorrhage (2.5-6.5) HR is 1.9, 95% CI is 1.1-3.1), subenstrial hematoma (HR is 2.3, 95% CI is 1.1-4.9) and desteteaptic valve decompression (HR is 4.2, 95% CI is 2.4-7.3).
although 94% of patients received anti-epileptic medication after the first LS, 85 patients (70% of LS patients) had recurrent seizures during follow-up.
, about one in ten CVT patients developed LS during the two-year mid-follow-up period.
risk of LS in patients with baseline intracranial hemorrhage, acute symptomatic seizures, and de-bone valve decompression.
.