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Neurology: A powerful biomarker for stroke prognosis-low brown-yellow outer mitochondrial DNA copy number (mtDNA-CN) may be related to poor baseline severity and prognosis after 1 month!

 Last Update: 2022-01-07
 Source: Internet
 Author: User

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Mitochondrial health plays an important role in the occurrence and recovery of stroke .

To answer these questions, researchers have recently investigated the relationship between measured and genetically predicted mtDNA-CN levels and the prognosis of stroke

A 1 standard deviation (SD) reduction in baseline mtDNA-CN was associated with stroke severity (baseline MRS; OR=1.

Source: Chong MR, Narula S, Morton R, et al.

Chong MR, Narula S, Morton R, et al.
Mitochondrial DNA Copy Number as a Marker and Mediator of Stroke Prognosis: Observational and Mendelian Randomization Analyses [published online ahead of print, 2021 Dec 8].
Neurology.
2021;10.
1212/WNL.
0000000000013165.
doi:10.
1212/WNL.
0000000000013165

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