 Home > Active Ingredient News > Study of Nervous System > Neurology: A pooled analysis of ATACH-2 and MISTIE III clinical trials—patients with primary intracerebral hemorrhage with underlying small vessel disease have less blood loss, a lower chance of hematoma expansion, or a better prognosis

Neurology: A pooled analysis of ATACH-2 and MISTIE III clinical trials—patients with primary intracerebral hemorrhage with underlying small vessel disease have less blood loss, a lower chance of hematoma expansion, or a better prognosis

 Last Update: 2022-01-21
 Source: Internet
 Author: User

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A significant proportion of patients with intracerebral hemorrhage have underlying small vessel disease (CSVD)

However, the relationship between CSVD markers and acute hematoma characteristics is poorly understood, and studies have produced conflicting results

Brain magnetic resonance imaging (MRI) scans were performed on the subjects

Of the 1499 non-hereditary stroke patients enrolled in the parent-child trial, 466 (31.

Our findings are consistent with the hypothesis that, in a cohort of patients with ICH, more severe underlying small vessel disease, represented by CMBS, results in a smaller baseline hematoma volume and reduced hematoma expansion

This study provides class II evidence that microbleeds on magnetic resonance imaging are associated with smaller hematomas in intracerebral hemorrhages and lower rates of hematoma expansion on subsequent imaging

Magid-Bernstein JR, Li Y, Cho SM, et al.

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