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| The latest international research: the neuronal specialization of human gastrulation stage has not yet begun |
China News Service, Beijing, November 18 (Reporter Sun Zifa) The world-renowned academic journal "Nature" recently published an embryology research paper.
Detailed cellular and molecular studies have found that the cellular specialization of the nervous system has not yet begun at this stage of development
.
The paper stated that gastrulation is an important event in the early stages of human development.
This stage is critical to human development, but it is sometimes difficult to study
.
The latest research results have brought a unique understanding of this
According to reports, as a decisive moment in the early stages of human development, the process of gastrulation begins about 14 days after fertilization and lasts about a week
.
The current understanding of the formation of human gastrulation in the academic world is basically limited to experimental models, and it is impossible to directly conduct research on it, because it is difficult to obtain human embryos at this stage.
The corresponding author of the paper, Shankar Srinivas, University of Oxford, UK, and colleagues analyzed a human embryo that was donated for research after voluntary termination of pregnancy.
The embryo is at a stage equivalent to the 16th after fertilization.
To 19 days
.
They described the cell types in the embryo and the genes expressed by these cells in detail, and compared them with experimental models
In this study, the author of the paper detected primordial germ cells (stem cells that become egg or sperm cells) and red blood cells
.
They also found that the cellular specialization of the nervous system has not yet begun at the developmental stage of gastrulation
"Nature" published a "News and Views" article at the same time and pointed out that although the paper only studied one embryo, the results of the study provided a new background for the experimental interpretation of other model systems
.
At the same time, these data also provide unique insights into the formation of human gastrulation, a previously unexplored basic stage of human embryo development
