NEJM: Leva saban for venous thrombosis prevention after lower limb orthopaedic surgery
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Last Update: 2020-06-24
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Source: Internet
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Author: User
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Non-major lower-body orthopaedic plastic surgery can lead to a brief decline in the patient's mobility, or even vein thromboembolism, and the prevention effect of delavsaban may be comparable to ennocosinrecently, researchers recruited adult patients with non-major orthopaedic orthopathic surgery on the lower extremities to randomly accept delavsabane or ennohexanThe main endpoints of the study were symptomatic far-end or near-end deep vein thrombosis, pulmonary embolism, venous thrombosis-related death sorcing or asymptomatic near-end deep vein thrombosis3,604 patients participated in the study, of whom 1,809 were treated with Delava ban and 1,795 were treated with enoxparinIn 4 of the 1661 patients in the Delavasa class (0.2%), 18 (1.1%) of the 1640 patients in the Enochparin group had large vein thromboembolism (multiple risk ratio 0.25)There was no significant difference in the incidence of bleeding in the delavata group and the ennoheparin group (1.1% and 1.0% of the main bleeding rate were 1.1% and 1.0%, respectively, while the main bleeding rates were 0.6% and 0.7%, respectively)studies have shown that delavsaban's effect on venous thrombosis is better than that of ennoheparin after non-major orthopaedic surgery in the lower extremities
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