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    Home > Active Ingredient News > Study of Nervous System > NEJM: Left atrial appendage occlusion in patients with atrial fibrillation can effectively prevent stroke

    NEJM: Left atrial appendage occlusion in patients with atrial fibrillation can effectively prevent stroke

    • Last Update: 2021-05-21
    • Source: Internet
    • Author: User
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    Brain stroke is the leading cause of death of Chinese residents , due to atrial fibrillation, cardiogenic stroke as one of the high incidence and type a great harm, serious harm to national health, increased social burden.


    Brain stroke is the leading cause of death of Chinese residents brain stroke is the leading cause of death of Chinese residents Stroke prevention of vascular

    Atrial fibrillation (atrial fibrillation) is one of the most common types of medsci.


    medsci.


    The early stage within 14 days after the onset of cardiogenic stroke caused by atrial fibrillation is not only a high-risk period for recurrence of stroke, but also a high-risk period for cerebral hemorrhage.


    The early stage within 14 days after the onset of cardiogenic stroke caused by atrial fibrillation is not only a high-risk period for recurrence of stroke, but also a high-risk period for cerebral hemorrhage.


    Researchers conducted a multi-center randomized trial involving atrial fibrillation who planned to undergo cardiac surgery for other reasons and a CHA2DS2-VASc score of at least 2 points (the score ranges from 0 to 9, the higher the score, the greater the risk of stroke) Participants.


    Surgery diagram

    Surgery diagram

    The main analysis population included 2379 participants in the occlusion group and 2391 participants in the non-occlusion group, with an average age of 71 years and an average CHA2DS2-VASc score of 4.


    114 participants (4.


    The plug group can reduce the risk of stroke by 33% (HR=0.


    Cumulative risk of stroke in the non-occlusion group (red) and the occlusion group (blue)

    Cumulative risk of stroke in the non-occlusion group (red) and the occlusion group (blue)

    In summary, patients with atrial fibrillation undergoing left atrial appendage occlusion can reduce the risk of ischemic stroke or systemic embolism.


    In summary, patients with atrial fibrillation undergoing left atrial appendage occlusion can reduce the risk of ischemic stroke or systemic embolism.


    references:

    Richard P.


    Left Atrial Appendage Occlusion during Cardiac Surgery to Prevent Stroke.
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