NEJM: Blood type, gene may affect the chance of severe COVID-19.

, June 23, 2020 /
PRNewswire/
-- A newgeneticstudy has found that if a person is infected with a new coronavirus, his genes and blood type may determine his chances of developing a more severe new coronavirusstudy, published online June 17 in the New England Journal of Medicine, helps confirm earlier, more interesting evidence that blood type is associated with an improvement or deteriorationnow, a team of researchers in Europe has found that people with type A blood have a 45 percent higher risk of contracting coronavirus estrain and developing co-condition-19 concurrent respiratory failure than people with other blood typesOn the other hand, people with type O blood had a 35 percent lower risk of developing this type of more severe COVID-19humans have four main blood types: Type A, B, AB and OPhoto Source: It's not clear why blood type affects susceptibility to serious illnessesDrRobert Glatter, an emergency physician at Lenox Hill Hospital in New York City, points out that genes that control blood types also play a role in the composition of the cell's surfaceChanges in the surface structure of cells may affect the vulnerability of cells to infection with the new coronavirus, he said"
We also know from previous studies that blood type affects blood clotting risk," he said"
the new study was conducted by a multi-agency team of genetic researchers, known as the COVID-19 severe GWAS group They analyzed the genes and blood types of more than 1,600 PATIENTs with COVID-19 from Italy and Spain, as well as more than 2,200 healthy controls in addition to the blood type findings, the team also found that certain gene clusters were associated with a higher chance of severe COVID-19 The group reported that such clusters increased the risk by 77 percent Glatter says genetic from European studies could also provide new targets for the search for the COVID-19 vaccine cases have risen in many states
while states such as Arizona, Florida and Texas have all hit new highs in the past few weeks after reopening 2,783 new cases were reported in Florida, 2,622 in Texas and 2,392 in Arizona, the New York Times reported Tuesday The three Sunshine Belt states are among 20 that have seen an increase in cases in the past two weeks Florida Governor Ron DeSantis told a news conference that the increase in florida was largely due to broader testing But epidemiologists say the real reason is the increased spread as businesses such as restaurants and bars reopen to support their claims, epidemiologists point out that in many states, the number of coronary virus hospitalizations and the percentage of positive tests have risen at the same time in states with an increase in COVID-19 cases, concerns about hospital bed capacity are growing But Texas Gov Greg Abbott believes the state's hospitals still have a large capacity, despite 2,519 hospitalizations for the disease, the Times reported new state, the epicenter of the U.S flu pandemic, Governor Cuomo warned Sunday that the state could restore the blockade as of Thursday, there have been more than 2.1 million cases of coronavirus infection and more than 117,000 deaths in the United States , though, there was some good news on Tuesday A widely used cheap steroid, dexamethasone, appears to reduce the death rate of patients with mechanically ventilated COVID-19 by a third, researchers at Oxford University in the UK have announced It also reduced the death rate by a fifth for patients who needed oxygen (but have not yet used a ventilator), the Times reported "That's at least good news," Dr Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, told The Associated Press "This is a major improvement in our existing treatment options." search for a vaccine
while research into an effective vaccine continues The U.S Department of Health and Human Services said in late May that it would provide up to $1.2 billion to AstraZeneca Pharmaceuticals to develop a possible coronavirus vaccine at Oxford University in the United Kingdom photo source: The fourth and largest vaccine research agreement funded a clinical trial of a potential vaccine in the United States this summer
involving about 30,000 volunteers, the Times reported what is our goal? The U.S Department of Health and Human Services said in a statement that at least 300 million doses of the vaccine could be produced as early as October the United States has agreed to provide up to $483m to biotech company Moderna and $500m to Johnson and Johnson to develop vaccines China has also provided $30 million to a viral vaccine project led by France's Sanofi, the New York Times reported Moderna said large-scale clinical trials of candidate vaccines will begin in July as of Thursday, according to the New York Times, the five states with the highest number of cases of coronavirus were New York, with nearly 390,000 people; New Jersey, nearly 168,000; California, with a population of more than 163,000; and In for More than 135,000 in Illinois, where more than 106,000 people countries are battling the pandemic
the situation remains dire in other parts of the world Although the outbreak has eased in parts of Europe and Asia, the outbreak in India is worsening Despite the surge in cases, the country has relaxed some of the social distances imposed in the world's largest confinement As of Thursday, there were nearly 367,000 cases in India, according to Johns Hopkins University Brazil has also become a hot spot for the coronavirus epidemic, with more than 955,000 cases confirmed as of Thursday, according to Hopkins University U.S President Donald Trump has issued a ban on all foreign visitors from Brazil, cnn reported, as a surge in cases of new pneumonia in brazil cases in Russia are also soaring: as of Thursday, Russia reported more than 560,000 CASES of COVID-19, the third highest in the world, according to Hopkins University Nearly 8.4 million people were reported to have been infected globally On Thursday, according to Hopkins University, of which nearly 450,000 died (BioValleyBioon.com) References: Blood type, genetics impact for severe COVID-19: study
David Ellinghaus et al Genomewide Association Study Severe of Covid-19 with The New England Journal of Medicine DOI: 10.1056/NEJMoa2020283
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