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This article is the original of Translational Medicine Network, please indicate the source for reprinting
Written by Jevin
According to the latest Global Atlas of Diabetes released by the International Diabetes Foundation (IDF), the global prevalence of adult diabetes is 9.
3%, and it is expected to reach 10.
9%
by 2045.
Overweight, obesity, unbalanced eating habits and physical inactivity are the main risk factors
for type II diabetes (T2D).
Recently, a study of nearly 80,000 people showed that higher fresh fruit intake and frequency of intake can prevent the occurrence of T2D, especially in NGT, but not in prediabetes, that is, increase the intake of fresh fruit to prevent T2D
in people with normal blood sugar.
https://link.
springer.
com/article/10.
1007/s00394-022-02998-6
Research background
01
Dietary fresh fruit intake is associated
with its high levels of vitamins, potassium, dietary fiber and carotenoids on coronary heart disease, stroke, certain cancers and associated mortality.
Dietary guidelines recommend increasing fresh fruit intake, especially overall fruit intake, as an important component of
healthy eating patterns across regions and ethnicities.
However, there is still a lack of uniform conclusions
on the association between fresh fruit consumption and diabetes risk.
Several prospective studies have shown no significant association between the incidence of T2D and fruit and vegetable intake in combination, while other meta-analyses and systematic reviews have found an inverse association
between fruit consumption and T2D risk.
In addition, little is known about the effects of fruit intake on people in different states of sugar metabolism
.
Prediabetes is known to develop T2D at different rates and is the main backup force
for diabetes.
Specific dietary patterns, such as meat diets and fried foods plus staples (low in fresh fruit), have been reported to be associated
with prediabetes.
Whether fruit consumption affects progression from normal blood sugar or prediabetes to T2D has not been studied
.
Research process
02
Participants in the study are from the ongoing China Cardiometabolic Diseases and Cancer Cohort (4C) study, a multicenter, population-based prospective cohort study
.
A total of 193,846 people attended baseline check-ups and 170,240 (87.
8%) completed follow-up, including short questionnaires designed to collect information on major disease conditions and on-site follow-up examinations
including blood sampling 。 In the analysis, the researchers further excluded missing food frequency questionnaire data (n = 15,843), failure to answer questions about fresh fruit consumption (n = 25,458), death during follow-up (n = 1858), known diabetes or glucose metabolic status not determined at baseline (n = 34,724), cardiovascular disease and cancer at baseline (n = 34,724), cardiovascular disease and cancer at baseline (n = 1490), or those who failed to attend the on-site follow-up examination but obtained information on major disease status through a short questionnaire (no blood sampling at follow-up, n = 11,305).
Finally, this analysis included 79,922 non-diabetic patients at baseline and identified 5886 diabetes events
during follow-up.
Study results
03
Studies have shown that eating fresh fruit is linearly and dose-dependent inversely associated with the risk of diabetes, with each additional 2 taels (100 g) of fruit eaten per day reducing the risk
of diabetes by 2.
8%.
However, this anti-diabetic benefit of eating more fruit (> 7 times a week) is mainly beneficial to people with normal blood sugar, but not in people with prediabetes
.
In addition, a study of nearly 20,000 people conducted by Wu Ming and Su Jian of the Jiangsu Provincial Center for Disease Control and Prevention found that diabetic patients eat more fresh fruits on weekdays, but help to better control blood sugar
.
A prospective study of chronic diseases in China, which included 500,000 Chinese people, also showed that eating more fresh fruits could not only reduce the risk of diabetes in the population, but also reduce the risk of microvascular complications by 28% and macrovascular complications by 13% in patients with type II diabetes
.
Resources:
https://link.
springer.
com/article/10.
1007/s00394-022-02998-6
Note: This article is intended to introduce the progress of medical research and cannot be used as a reference
for treatment options.
If you need health guidance, please go to a regular hospital
.
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