Nature Sub-Journal: Your DNA will determine when you have sex for the first time and when you become a parent

The topic of the related research is "Identify 371 genetic variants related to first-time sexual behavior and age at birth and externalization behavior".

As the largest study in this field so far, scientists from the above-mentioned institutions have participated in the study of nearly 1 million people and collected sample information of 387,388 first-time sexual behaviors and 542,901 first-time reproductive behaviors in combination with multiple data sources

Later, by using genome-wide association analysis (GWAS), they found autosomal single nucleotide polymorphisms (SNPs) sites, which, together with our environmental factors, affect two milestones in people’s lives ——The age of first sex and the age of parenting for the first time!

*Note: SNP refers to the diversity of DNA sequences caused by changes in single nucleotides (A, T, C, G) at the genome level

Among the 371 gene mutation sites, 282 are related to the "first night" age, and 89 are related to the "first birth" age

This discovery can be described as "accidental but reasonable"-when we have the first sexual behavior, when we have children, in fact, it is not only affected by social and environmental factors, but even mixed with some "Destined"

Based on these newly discovered genetic markers, the researchers calculated a polygenic score (PGS), and the results showed that individuals with higher PGS tended to delay their first intercourse and childbirth

In addition, these genetic effects are also closely related to environmental factors: children with higher socioeconomic status (i.

Researchers have also found that people who are genetically inclined to postpone sex or have a late childbirth are in better health and live longer in old age

Other factors such as tobacco and alcohol, drugs, ADHD, loneliness, education level, precocious sex and fertility are also closely related

The use of AFS and AFB to measure the start time of human reproductive behavior also has an important impact on reproductive health, adolescent development and evolutionary health

Studies have shown that premature sex is an important factor in inducing cervical cancer: Compared with women 21 years of age or older who have sex on the first night, women under 17 have twice the risk of cervical cancer

In addition, depression, sexually transmitted diseases and drug abuse disorders are also related to it

This study shows that genetic signals are driven by social factors and environment, as well as reproductive biology

The combined effect of the three determines the advancement and postponement of the reproductive period

This research has discovered hundreds of genetic markers that shape the most basic part of our lives and have the potential to gain a deeper understanding of adolescents’ mental and sexual health, infertility and later life diseases, to help develop corresponding Of treatment
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The New Year is about to come.
The above research results may be able to resist some of the offensives of "marriage urging" and "childbirth" for you
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Remember, good luck .

Original search:

[1] Nature Human Behaviour:

Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour

https://doi.
org/10.
1038/s41562-021-01135-3

[2] British Journal of Cancer:

Comparison of risk factors for squamous cell and adenocarcinomas of the cervix: a meta-analysis

https://doi.
org/10.
1038/sj.
bjc.
6601764