Nature sub-journal: Scientists have mapped the body's immune response to the new coronavirus for the first time.

Australian researchers published novel coronavirus immunoreactive maps in the latest Nature Medicine magazine, which is similar to seasonal influenza, which is a potential breakthrough in the fight against this global killer.this paper reported the clinical and virological characteristics of a mild to moderate covid-19 patient who needed to be hospitalized.this case is a 47 year old female patient from Wuhan City, Hubei Province, China. Before symptom recovery, increased antibody secreting cells (ASCs), follicular helper T cells (TFH cells), activated CD4 + T cells and CD8 + T cells, as well as immunoglobulin M binding to coronavirus sars-cov-2, were detected in her blood before symptoms recovered IgM and IgG antibodies, these immune changes lasted at least 7 days after the symptoms completely disappeared.these are "very similar to what we see in flu patients," the researchers said.the emergence of immune response during non severe symptomatic covid-19 has two practical applications.first, it will help virologists develop vaccines because the purpose of vaccination is to replicate the human body's natural immune response to the virus; and the second practical application is screening, which can help health authorities better predict who is at risk in future outbreaks.most covid-19 deaths occur in elderly patients or in patients with heart disease, diabetes and other diseases. Children seem to have few or no symptoms, which requires more research to find out the cause, but the immune system does slow down naturally with age.in general, this study provides a new contribution to understanding the breadth and dynamics of the immune response in non severe covid-19 cases.the researchers recommend identifying the characteristics of these immune parameters in the covid-19 population with different disease severity to determine whether they can be used to predict disease outcomes, evaluate new interventions that may minimize severity and inform protective candidate vaccines.end reference: [1] doctors map body's coved-19 immune response: study [2] bread of consistent immune responses prior to patient recovery: a case report of non-severe coved-19