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"We have shown how the proteins Pou5f3 and Sox19b function at different time points in embryonic development and in different regions of the embryo," said the biologist who studied the integrated approach
is an important molecule in stem cell research
Similar human proteins, so-called homologues of Pou5f3 and Sox19b, were used in studies to artificially create stem cells from human skin cells
To determine precisely which genes the two proteins control in what way, and how they interact, the biologist and her team studied the development of zebrafish embryos
Genetic control in sleep patterns
In addition, the team found that Pou5f3 and Sox19b can repress late-stage gene programs
Journal Reference :
Meijiang Gao, Marina Veil, Marcus Rosenblatt, Aileen Julia Riesle, Anna Gebhard, Helge Hass, Lenka Buryanova, Lev Y.