Nature: Release! Metastasis map of human cancer cells 

Human cancer cell lineage has been a driving force in cancer research, helping researchers discover a variety of carcinogenic mechanisms and therapeutic targets.
, however, large-scale symptoms of cell line are limited to basic readings, such as survivability in cell culture systems.
, more complex ideolyts, such as the behavior of tumor cells in the body, have been unable to be scaled up.
, tumor metastasis in most studies relies on only a few experimental models, making it difficult to extratrot conclusions to genetically diverse human tumors.
Recently, researchers published a paper in the journal Nature that they have introduced an in vivo bar code strategy that can determine the metastasis potential of human cancer cell lines in mouse foreign transplants on a large scale and apply it to 500 cell lines and across 21 types of solid tumors, verifying the robustness, scalability and repeatability of the method.
researchers created the first generation of metastasis maps (MetMaps), revealing organ-specific transfer patterns that are associated with clinical and genomic characteristics.
researchers demonstrated metMap's effectiveness by studying the molecular basis of breast cancer that can be transferred to the brain, one of the main causes of death.
breast cancer, which can be transferred to the brain, shows evidence of changes in lipid metabolism.
the disturbance of lipid metabolism in these cells inhibited the development of brain metastasis, proposed a treatment strategy to prevent and treat diseases, and demonstrated the effectiveness of MetMap as a resource to support transfer research.
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