Nature leads the way!

Time flies like a white horse, and the process of 2022 is already halfway through
.
Despite the repeated epidemics, the scientific field is still in full bloom and has achieved remarkable results.
Many research results related to proteomics and metabolomics have been published in various SCI journals with high scores, and the field of life sciences and precision medicine has been continuously promoted.
The vigorous development
.


Zhongke New Life has been deeply involved in the application and development of multi-omics such as proteomics and metabolomics, and is very honored to participate in the scientific research of a number of omics studies
.
According to incomplete statistics, in the first half of 2022, a total of 211 omics articles were published by clients of Zhongke New Life, including Nature, Signal Transduction and Targeted Therapy, Nature Communications, The Journal of Clinical Investigation, Advanced Science, etc.
There are 31 articles with more than 10 points in total, with a cumulative impact factor of 1441.
95 points and an average impact factor of 7.
39 points.

Next, I will follow the editor to take stock of the high-scoring articles in the first half of 2022.
While congratulating these research teams, I also hope to provide some ideas and help for teachers' future research plans
.


01 Protein article
# 01
Document name: NLRs guard metabolism to coordinate pattern- and effector-triggered immunity
Publication journal: "Nature" (IF=69.
504)
Cooperative unit: Chinese Academy of Sciences Center for Excellence in Molecular Plant Science and Innovation
Service content provided by Zhongke Xinsheng : Proteomics
 
# 02
Document name: The Eph receptor A4 plays a role in demyelination and depression-related behavior
Journal: "The Journal of clinical investigation" (IF=19.
456)
Cooperative unit: Mental Health Center Affiliated to Shanghai Jiaotong University School of Medicine
The content of services provided by Zhongke New Life: Proteomics
 
# 03
Document name: HTR1A Inhibits the Progression of Triple‐Negative Breast Cancer via TGF‐β Canonical and Noncanonical Pathways
Publishing journal: Advanced Science (IF=17.
521)
Cooperative unit: Fudan University Affiliated Cancer Hospital
Chinese New Life Service Content: Adhesive Strip Protein Identification
 
# 04
Document name: CD73 in small extracellular vesicles derived from HNSCC defines tumor-associated immunosuppression mediated by macrophages in the microenvironment
Published journal: "Journal of Extracellular Vesicles" (IF=17.
337)
Cooperative unit: Shanghai Ninth People's Hospital
Zhongkexin Service content provided by life: protein shotgun analysis
 
# 05
Document name: Peroxidase from foxtail millet bran exerts anti-colorectal cancer activity via targeting cell-surface GRP78 to inactivate STAT3 pathway
Publication journal: "Acta Pharmaceutica Sinica B" (IF=14.
903)
cooperation Unit: School of Life Sciences, Shanxi University
Service Content: Protein Identification
 
# 06
Title: The potential role of plasma membrane proteins in response to Zn stress in rice roots based on iTRAQ and PRM under low Cd condition
Publication journal: 《 Journal of Hazardous Materials (IF=14.
224)
Cooperative unit: China Rice Research Institute
Service content provided by Zhongke New Life: Protein Quantitation (iTRAQ)
 
# 07
Document name: Exogenous melatonin alleviates NO2 damage in tobacco leaves by promoting antioxidant defense, modulating redox homeostasis, and signal transduction
Published journal: " Journal of Hazardous Materials” (IF=14.
224)
Cooperative unit: Northeast Forestry University School of Life Science
Zhongke Xinsheng Service Content: Proteomics
 
# 08
Title: Quantitative proteomics and phosphoproteomics elucidate the molecular mechanism of nanostructured TiO2-stimulated biofilm formation
Published journal: "Journal of Hazardous Materials" (IF=14.
224)
Cooperative unit: School of Environment and Resources, Xiangtan University
Service content provided by Zhongke New Life : Proteomics + Phosphoproteomics
 
# 09
Title: Toxicological effects of tris (1, 3-dichloro-2-propyl) phosphate in oyster Crassostrea gigas using proteomic and phosphoproteomic analyses
Publication: Journal of Hazardous Materials (IF=14.
224)
Cooperative unit: Coastal Environmental Process, Chinese Academy of Sciences Key Laboratory of Ecological Restoration and Ecological Restoration
Services provided by Zhongke New Life: Proteomics + Phosphorylated Proteomics
 
# 10
Title: Fine‐tuning of SUMOylation modulates drought tolerance of apple
Published journal: Plant biotechnology journal (IF= 13.
263)
Cooperative unit: State Key Laboratory of Crop Stress Biology in Arid Regions (Northwest A&F University)
Service content provided by Zhongke New Life: Proteomics
 
# 11
Document name: Phospholipase A2 inhibitor and LY6/PLAUR domain-containing protein PINLYP regulates type I interferon innate immunity
Published journal: "PNAS" (IF=12.
78)
Cooperative unit: Key Laboratory of Molecular Virology and Immunology, Pasteur Institute, Shanghai, Chinese Academy of Sciences
Service content provided by New Life: Proteomics
 
# 12
Title of the paper: Overexpressed integrin alpha 2 inhibits the activation of the transforming growth factor β pathway in pancreatic cancer via the TFCP2-SMAD2 axis
Published journal: "Journal of Experimental & Clinical Cancer Research" (IF=12.
658)
Cooperative unit: Tongji, Huazhong University of Science and Technology Xiehe Hospital Affiliated
to the Medical College Chinese Science and Technology New Life Service Content: Protein Profiling
 
# 13
Title: A Ralstonia solanacearum effector targets TGA transcription factors to subvert salicylic acid signaling
Publishing journal: "The Plant Cell" (IF=12.
085)
Cooperative unit :
Service provided by Zhongke New Life, School of Plant Science and Technology, Huazhong Agricultural University Content: Protein Identification
 
# 14
Literature Title: NUMB facilitates autophagy initiation through targeting SCFβ-TrCP2 complex
Published Journal: "Cell Death & Differentiation" (IF=12.
067)
Cooperative Unit ：Department of Nephrology, Nanfang Hospital, Southern Medical University
Service content provided by Zhongke New Life: Proteomics
 
#15
Literature name: O-GlcNAcylation and stablization of SIRT7 promote pancreatic cancer progression by blocking the SIRT7-REGγ interaction
Published journal: "Cell Death & Differentiation" (IF=12.
067)
Cooperative unit: The Second Affiliated Hospital of Zhejiang University School of Medicine
, Zhongke Xinsheng Content of services provided: O-GlcNAc glycosylation modification
 
# 16
Title of document: An unexpected role for BAG3 in regulating PARP1 ubiquitination in oxidative stress-related endothelial damage
Publication journal: "Redox Biology" (IF=10.
787)
Cooperation unit: Chinese Medical Science University Health Science Research Institute
, China Science and Technology New Life Service Content: Proteomics
 
#17
Title: An integrated multi-omics approach revealed the regulation of melatonin on age-dependent mitochondrial function impair and lipid dyshomeostasis in mice hippocampus
Published in the journal: " Pharmacological Research" (IF=10.
334)
Cooperative unit: School of Life Science and Biopharmaceuticals, Shenyang Pharmaceutical University
Service content provided by Zhongke Xinsheng: DIA Proteomics
 
02 Metabolism and Lipid Chapter
# 01
Title: Thrombin induces ACSL4-dependent ferroptosis during cerebral ischemia/reperfusion
Published journal: "Signal Transduction and Targeted Therapy" (IF=38.
104)
Cooperative unit: West China Hospital, Sichuan University
Service content provided by Zhongke New Life: Lipidomics
 
# 02
Document name: Mechanical force promotes dimethylarginine dimethylaminohydrolase 1-mediated hydrolysis of the metabolite asymmetric dimethylarginine to enhance bone formation
Published journal: "nature communications" (IF=17.
694)
Cooperative unit: Zhejiang University School of Medicine
, Zhongke New Life Service Content: Metabolomics
 
# 03
Title: Gut microbiota regulates acute myeloid leukaemia via alteration of intestinal barrier function mediated by butyrate
Published journal: "Nature Communications 》（IF=17.
694）
Cooperative unit: Qilu Hospital of Shandong University
The content of services provided by Zhongke New Life: Non-target metabolism
 
# 04
Document name: Response mechanism of psychrotolerant Bacillus cereus D2 towards Ni (II) toxicity and involvement of amino acids in Ni (II) toxicity reduction
Published journal: "Journal of Hazardous Materials" ” (IF=14.
224)
Cooperative unit: College of Resources and Environment, Jilin Agricultural University
Service content provided by Zhongke New Life: Metabolomics
 
# 05
Title of document: Multi-omics analysis reveals the molecular responses of Torreya grandis shoots to nanoplastic pollutant
Publication journal: "Journal of Hazardous Materials" (IF=14.
224)
Cooperative unit: School of Forestry and Biotechnology, Zhejiang Agriculture and Forestry University
Service content provided by New Life: Plant Metabolome
Article Interpretation Link: Project Article J Hazard Mater (IF 10.
588) | Multiple groups Scientific Analysis Reveals Molecular Response Mechanism of Torreya Torreya Seedlings to  Nanoplastic Pollutants
 
# 06 Title: Cadmium perturbed metabolomic signature in pancreatic beta cells correlates with disturbed metabolite profile in human urine Published journal: "Environment International" (IF=13.
352)
Cooperative unit: The First Affiliated Hospital of Zhejiang University School of Medicine
Service content provided by Zhongke New Life: Metabolomics
 
# 07
Document name: Riboflavin integrates cellular energetics and cell cycle to regulate maize Journal of seed development
: "Plant Biotechnology Journal" (IF=13.
263)
Cooperative unit: College of Agriculture, Henan Agricultural University
Service content provided by Zhongke New Life: Targeted Metabolism
 
# 08
Title: Lipid reprogramming induced by the TFEB-ERRα axis enhanced membrane fuidity to promote EC progression
Journal of publication: "Journal of Experimental & Clinical Cancer Research" (IF=12.
658)
Cooperation unit: Fujian Medical University Affiliated Hospital, Fujian Maternal and Child Health Hospital
, Zhongke Xinsheng Service content: lipidome + metabolism Panel
 
#09
Title: Multi-stage metabolomics and genetic analyses identified metabolite biomarkers of metabolic syndrome and their genetic determinants
Published journal: "EBioMedicine" (IF=11.
205)
Cooperative unit: Department of Epidemiology and Statistics, School of Public Health, Zhejiang University
Service content provided by Zhongke New Life: Metabolomics
 
# 10
Title: Metabolomics reveals that CAF-derived lipids promote Colorectal cancer peritoneal metastasis by enhancing membrane fluidity
Published journal: "International Journal of Biological Sciences" (IF= 10.
75)
Cooperative unit: The Sixth Affiliated Hospital of Sun Yat-Sen University
Service content provided by Zhongke New Life: Lipidomics
 
# 11
Literature name: Lower abundance of Bacteroides and metabolic dysfunction are highly associated with the post-weaning diarrhea in piglets
Publication journal: "Science China Life Sciences" (IF= 10.
372) Cooperative unit: Service content provided by Zhongke Xinsheng
, Institute of Animal Nutrition, Sichuan Agricultural University
: Off-target Metabolism and Data Analysis
 
03 High-throughput Sequencing
# 01
Title: Targeted delivery of Chinese herb pair-based berberine/tannin acid self-assemblies for the treatment of ulcerative colitis
Published Journal: "Journal of Advanced Research" (IF= 12.
822)
Cooperative unit: Macau University of Science and Technology State Key Experiment on Quality Research in Chinese Medicines
Service content provided by Zhongke New Life: 16s sequencing 04 Multi -
 
omics joint article
# 01
Document name: Seasonal variations and feedback from microplastics and cadmium on soil organisms in agricultural fields
Publication journal: "Environment International" (IF= 13.
352)
Cooperation Unit: School of Environment, Nanjing University
Service Contents Provided by New Life: 16s+ Metabolomics
Article Interpretation Link: Project Article | 16S+ Metabolism Helps Customers' Soil Pollution Research Landed in the Top Journal of Environmental Science  Hope the
 
above sharing can bring some benefits to researchers Scientific research ideas, and hope that our products and services can provide you with more valuable help
.
In addition, teachers who are interested in our high-scoring customer articles above can send us a private message, and we will organize and package them and send them to you after statistics
.
Finally, I wish all teachers and students to continue to work hard in the second half of 2022 and to publish high-level SCI papers as they wish!