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Our brains are extremely complex and perform countless complex processes that allow us to think, move and feel
Researchers at the Max Planck Institute for Neurobiology have recently studied how this diversity occurs
The human body is composed of hundreds of types of cells, each of which has a specific function
Diversity is formed because cells do not need to use all genetic information
The fate of most cells is determined during development
There are many types of cells in the human brain, most of which are glial cells and neurons
One problem that has so far been confusing is how human undifferentiated progenitor cells can produce such a huge cell diversity in just a few weeks, while mice even only need a few days
Researchers have developed a new technique to label progenitor cells
When the marked cell divides, it passes the barcode to its daughter cells so that it can identify which cells are its offspring
Researchers have found that it is impossible to make assumptions about developmental relationships based on cell types and their similarities: Contrary to popular belief, cells with similar cell types often cannot be traced back to a common origin during development
They even proved the opposite in inhibitory neurons: Even different cell types in different brain structures may come from the same progenitor cells
Researchers hope to use these results to better understand neurodevelopmental disorders
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Bandler, RC, Vitali, I.
