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A team led by researchers at the University of Texas Southwestern has determined how the SARS-CoV-2 virus that causes COVID-19 builds a structure called the RNA cap, which is critical to the virus's successful replication
"We are very excited to develop and manufacture targeting of this protein," said study leader Vincent Tagliabracci, PhD, associate professor of molecular biology, Michael L.
SARS-CoV-2 uses the genetic molecule ribonucleic acid (RNA) to give infected host cells instructions to make more copies of the virus
The new study shows that the NiRAN domain of SARS-CoV-2, part of a viral protein called nsp12, is involved in RNA cap synthesis
Dr.