Nat Neurosci: The loss of the surface genomics analysis of neurons in Parkinson's disease has a neuropersonal protective effect.

Parkinson's disease is a severe neurodegenerative disease involving sexual movement and non-motor symptoms, and more than 6 million people worldwide suffer from Parkinson's disease.
although the disease has many clinical manifestations consistent with the basis of presommic genetics, the vast majority of PD cases are iditable and the edigenesic mechanism is not clear.
mechanism is part of the dynamic means of gene regulation, representing the fusion characteristics of environment, aging and genetic risk factors.
PD clinical characteristics, such as delay in the age of onset of the disease, low consistent rate among single-egg twins (11%), fluctuations in symptoms during the course of the disease, manifestations of one- to two-sided symptoms in most people (85%)3 and significant risk of gender differences in the disease, together indicate the contribution of the alterable apparent genome to the origin and progression of the disease.
Although recent candidate genes and array-based studies have supported the occurrence of metagenetic abnormalities in PD tissues, so far the overt genomes of PD patients have not been fully studied, and the contribution of metagenetics to neuron dysfunction in the disease has not been sufficient.
early synaptic damage, neuron deposition of aggregation alpha-synaptic nucleoproteins, and gradual neurodegenerative changes in the black synth system are all signature pathological features of PD, suggesting that neurons are involved in the disease.
dna methylation, which is modified by metastable genetic modification, plays a key role in gene expression and neuron survival, which depends on activity.
(TET) enzyme catalytic DNA methylation to hydroxymethylation (and eventually demethylation), which has also been shown to affect neurodevelopment and... MedSci Original Source: MedSci Original Copyright Notice: All text, images and audio and video materials on this website that indicate "Source: Mets Medicine" or "Source: MedSci Originals" are owned by Mets Medicine and are not authorized to be reproduced by any media, website or individual, and are authorized to be reproduced with the words "Source: Mets Medicine".
all reprinted articles on this website are for the purpose of transmitting more information and clearly indicate the source and author, and media or individuals who do not wish to be reproduced may contact us and we will delete them immediately.
reproduce content at the same time does not represent the position of this site.
leave a message here.