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Nat Neurosci: Different neural bases that mediate tissue damage and allodynia caused by depression-like states

 Last Update: 2021-03-21
 Source: Internet
 Author: User

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Painful stimulation is the result of a series of complex and different combinations of etiology, genetic and environmental factors, which jointly participate in specific neurobiological processes.

In humans, both tissue damage and depression can lead to hyperalgesia, but whether this involves a different circuit is unclear.

Different thalamic cortical circuits are the basis for allodynia caused by tissue damage and depression-like states.

This study depicts independent thalamic cortical circuits that encode ectopic pain from tissue damage and depression-like states.

Original source:

Zhu Xia,Tang Hao-Di,Dong Wan-Ying et al.

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