Nat Med: Our scientists have pointed out that the immunity of asymptomatic neo-coronavirus infection sorority may be weaker than in patients with symptomatic infections.

, June 20, 2020 /
BiovalleyBIOON/--- In a new study, researchers from Chongqing Medical University in China, The Center for Disease Control and Prevention in Chongqing, Wanzhou District People's Hospital in Chongqing, and the Center for Disease Control and Prevention in Chongqing City found that people infected with SARS-CoV-2 (the new coronavirus that causes COVID-19) but did not show symptoms may have significantly lower levels of immunity to the virus than those with severe conditionsThe findings were published online June 18, 2020 in the journal Nature Medicine under the title "Clinical and immune assessmento of asymptomatic SARS-CoV-2 infections"images from Nature Medicine, 2020, doi: 10.1038/s41591-020-0965-6most people infected with the virus show relatively light signs of infection, and a small number of patients show no symptoms at allLittle is known about this group because they are less likely to be tested for subsequent severe symptoms, including respiratory problemsthe researchers compared two groups of patients infected with COVID-19 in Wanzhou District of Chongqing: 37 patients with symptoms and 37 patients withsymptomsthey analyzed blood samples taken by both groups of patients in the weeks after their recovery and found that only 62.2 percent of asymptomatic patients had short-term antibodies, compared with 78.4 percent of patients with symptomsAfter 8 weeks of recovery, the level of antibodies in 81.1% of asymptomatic patients decreased, compared with 62.2% in patients with symptomsWhat's more, they found that 18 asymptomatic anti-inflammatory cell signaling protein levels were lower than in patients with symptoms, suggesting that asymptomatic patients had a weaker immune response to the new coronavirusthe researchers say their findings question the idea that people who have been infected with the coronavirus are immune to future infections"These data may indicate the risk of using THE COVID-19'immune passport" and support extended public health interventions, including social distance, hygiene, isolation of high-risk populations, and extensive testing,", they wroteDanny Altmann, a spokesman for the British Society ofimmuno
logy and professor of immunology at Imperial College, who was not involved in the new study, said the study raises an important question in the fight against COVID-19 "So far, many of the immunology data have come from the most sick hospital patients analyzed, but most of the less affected people want to know if it has the potential to give lasting protective immunity," said Altmann said the significant drop in antibody levels in many patients in the study was "an important and potentially worrying issue." "Although the patient's sample size is small, this is in line with some people's concern that natural immunity to coronaviruses may last for a fairly short period of time," Altmann said (Bio Valley Bioon.com) Reference: quan-Xin Long et al , Clinical and immuneo sane assessment of asymptomatic SARS-CoV-2 Nature Medicine, 2020, doi: 10.1038/s41591-020-0965-6.
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