Nat Med: Blood tests help curb malaria transmission

March 20, 2020 /PRNewswire/---/2020 The most popular malaria parasite in the world, with up to 2 billion people at risk of infectionparasites not only cause disease and death during the "active" stage of infection, but can also remain hidden in the liver, in hibernation, and are an important cause of "malaria recurrence"(photo source:these dormant parasites are currently undetectable and can eventually lead to more than 80 percent of all blood-stage infectionsIdentification and targeted treatment are therefore critical to accelerating and achieving malaria eliminationin a recent study, the authors developed a set of serological markers that can classify patients with interstitastorioplasmosis infection with dormant potentialin a longitudinal clinical cohort studyThailand and Brazil, the authors measured the IgG antibody response of 342 interstitas and identified 60 possible exposed serological markers using the AlphaScreen systemvalidated candidate markers using samples from a one-year observational queue in Thailand, Brazil and the Solomon Islands, and had 80% sensitivity and specificity in the past nine months for antibody responses to eight interstitastic malaria parasite proteins classified as inter-japanese malaria parasite infectionsMathematical models show that serological detection and treatment strategies can reduce the prevalence of malaria parasites by 59-69%these eight antibody reactions can be used as biomarkers, and the test offers new opportunities to improve malaria control and elimination strategies(Bio Valley Bioon.com)Source:Blood Test offers new access to the improve malarial control and theof the original origins:Longley, RJ., et al(2020)Development and of the serological markers for the detecting Plasmodium vivaxNature Medicine.
doi.org/10.1038/s41591-020-0841-4.