Nat Genet: the study found nearly 50 new genes that increase the risk of breast cancer

July 24, 2018 / BIOON / - research shows that only a small part of breast cancer is caused by genetics, and researchers do not know most genes related to this disease And a new study points to several possible sensitive genes Image source: an international team at nephron / Wikipedia recently found that 48 genes are associated with an increased risk of breast cancer in women - 34 of which have been suggested in previous studies, while the remaining 14 are new genes The study was led by Professor Wei Shi of Lang Wu, UWM, and the beghoffer Institute of medicine, qimr, with more than 200 participants The study was recently published in Nature Genetics Using data science models that predict gene expression in breast cancer tissue and data from Cancer Genome Atlas, the researchers studied 229000 European descendants, some with and some without cancer The researchers further analyzed the genetic pathways involved in the biological processes that can go wrong in the development of breast cancer In the experiment, researchers found that after some genes were silenced, breast cancer cells stopped growing "This study perfectly illustrates how new statistical techniques can be used to find genetic factors associated with breast cancer." Auer, an associate professor of Biostatistics from UWM, said "The results of this study will deepen our understanding of breast cancer biology and genetics, and may help us to find better prevention and treatment strategies." Reference: Lang Wu et al A transcript wide association study of 229000 women identities new candidate probability genes for breast cancer, Nature Genetics (2018) Doi: 10.1038/s41588-018-0132-x