Nat Commun: Optogenetics can control monkey movement

, July 7, 2020 /PRNewswire/ -- Biovalley BIOON/--- Optogenetics is a recently developed genetic modification technique that can be genetically modified to import photosensitive proteins into cells and then control cell function by lighting cells that express photosensitive proteinsOptogenetics enables us to activate or inhibit a specific number of neuronal cellsToday, optogenetics has become an indispensable tool for studying brain functionSo far, most studies using this technique have been conducted in rodents, and all but a few studies of eye movement in monkeys have failed(Photo:a team led by Professor Atsushi Nambu of Japan's National Institute of Physiological Sciences and Professor Hajime Mushiake of Tohoku University successfully controlled the arm movement of Japanese macaques through optogeneticsThe study will be published in the journal Nature Communicationsfirst, the research team developed a adeno-related viral vector that effectively expresses photosensitive protein channel vision of recurrentThe team injected the virus vector precisely into the area of the cerebral cortex, which controls the movement of the arm, after previous studies showed that electrical stimulation of the area can cause significant arm movementThe team also developed a spectre that records neuronal activity and exerts light and electrical stimulation, respectivelyThe light stimulation of the aurora can effectively activate the neuronal cells that express the channel vision of recurrent matter and induce muscle movement and arm movementin all, the study opens the door to optogenetics research in non-human primates and for clinical applications in human patients, such as optical deep brain stimulation(Bio Valley Bioon.com)source:Researchers use optogenetics to successful lyi add arm movements in monkeys
original origin:Watanabe, H., et al (2020) Forelimb movements evoked by optogenetic of the macaque Nature Communications doi.org/10.1038/s41467-020-16883-5.