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Nat Commun: Infant gut microbial composition is related to non-social fear behavior

 Last Update: 2021-06-10
 Source: Internet
 Author: User

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Fear, a behavioral response to threats, is an evolutionary conservative mechanism that promotes survival.

At about 6 months of age, babies show fear processing by distinguishing fearful faces and other facial expressions.

Fear may be a regulatory or protective mechanism to balance the increase in movement and exploration behavior during this time.

Existing studies have shown that experimental manipulation of gut microbes in animal models has changed fear behaviors and related neural circuits.

The first year of life is a critical period for brain development, the appearance of fear, and the establishment of the gut microbiome.

The composition of the 1-year-old gut microbiome (Weighted Unifrac; lower abundance of Bacteroides, increased abundance of Veillonella, Dialister, and Clostridiales) is significantly related to the increase in fear behaviors in the non-social fear paradigm.

The relationship between infant microbiome and non-social fear behavior

Correlation between infant microbiome and non-social fear behavior Correlation between infant microbiome and non-social fear behavior

Babies with increased microbiome richness and decreased uniformity at 1 month also showed increased non-social fear.

This study shows the relationship between the human infant gut microbiome and fear behavior, and the possible relationship between fear-related brain structures , and it is based on a small group.

The relationship between the human infant gut microbiome and fear behavior, and the possible relationship between the brain structure related to fear, and the possible relationship between the human infant gut microbiome and fear behavior, and the possible relationship between the brain structure related to fear

Original source:

Alexander L.

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