Nat Biomed Eng's new breakthrough! Systemic tracking of single cells with PET/CT imaging

, July 9, 2020 /
Biovalley
BIOON /- Living molecular imagery can detect the movement dynamics and movement of injected cells throughout the body, but most existing methods are unable to accurately assess cell distribution due to the nonspecific distribution of contrast agents and the release of contrast agents out of the cellresearchers from the Department of RadiologicalOncology, Radiology, and Biology, led by Guillem Pratx, of Stanford University School of Medicine, developed a new method for accurately tracking individual cells throughout the body using posatron tom, based on the results of the study, published in the journal Nature Biomedical Engineering, entitled "Whole-body-all-all-type of science-of-cells-vector-vector-sit-on-the-body."Picture Source:In the study, Nat Biomed Eng, researchers found that by loading 68Ga-rich mediadratized siliconnano-
particles into individualbreast cancercells and injected into immunodeficiency mice, they could use positron emission tomography and X-ray computed tomography to monitor photon son-insized patterns and cell movement and distribution in real timeresults showed that the average speed of cell movement after the endofor intravenous injection was 50 mm/s, and 2-3 seconds after the endve vein entered the lungs, which is consistent with the rate of blood flowresearchers believe the single-cell tracking technique could be used to detect cell motor dynamics in earlytumor
metastasis, cell cell capture in metastatic cancer cells, tracing of immune cells during cancer immunotherapy, and post-immune cell transplantation(BioValleyBioon.com) References: Jung, K.O., Kim, T.J., Yu, J.H et al.
Whole-body tracking of single cells via positron emission tomography Nat Biomed Eng (2020) https://doi.org/10.1038/s41551-020-0570-5