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    Home > Active Ingredient News > Antitumor Therapy > Muscle exercise + aerobic exercise reduces the risk of cancer death by 28%!

    Muscle exercise + aerobic exercise reduces the risk of cancer death by 28%!

    • Last Update: 2022-04-27
    • Source: Internet
    • Author: User
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    *Read only for medical professionals Reference Fitness Benefit! In modern society, the pace of life is fast and the pressure is high.
    Most people go home and spread out on the sofa.
    Exercise has become a luxury! Little driver, let me do a survey first~ How many days a week do you exercise? According to the latest cancer data in China published by the Hejie academician team in JNCC in 2022, the number of people who lack exercise and obesity in China continues to increase, which has also led to an increase in the incidence of some malignant tumors such as breast cancer and colorectal cancer [1]
    .

    Obesity and lack of exercise in young drivers do increase the risk of certain malignancies
    .

    However, a recent study published in the BMJ sub-journal [2] confirmed that active muscle exercise reduces all-cause mortality from non-communicable diseases such as tumors! Figure 1 Screenshot of the study.
    A total of 16 prospective cohort studies on muscle-strengthening activity and risk of death and non-communicable diseases in adults ≥18 years of age were included.
    A systematic review and meta-analysis were conducted.
    , alcohol intake, and smoking history, and some studies adjusted for sex, ethnicity, dietary habits, disease history, and sociodemographic economics
    .

    All studies looked at both types of physical activity, aerobic and muscle-strengthening
    .

    The muscle strengthening of the little driver here is not heavy work or heavy lifting, but a real "fitness program"! Muscle-strengthening exercises include resistance exercise, strength training, and aerobics
    .

    One study looked at the relationship between exercise and cancer, and five studies looked at the relationship between exercise and cancer mortality
    .

    Muscle-strengthening exercise reduced overall cancer risk by 12% (RR=0.
    88; 95%CI 0.
    80-0.
    97; P=0.
    008), but the study was highly heterogeneous (I2=75.
    8%; P<0.
    001)
    .

    Figure 2 Four studies have investigated the relationship between duration of muscle-strengthening exercise and cancer risk
    .

    Although the results showed that there was no linear relationship between the duration of muscle strengthening exercises and overall cancer risk, there was a non-linear relationship (see graph below)
    .

    Figure 3 There is no linear relationship between the duration of muscle strengthening exercise and cancer riskFigure 4 There is a non-linear relationship between muscle strengthening exercise and cancer risk.
    Muscle strengthening exercise for 30 minutes per week has the lowest relative risk (RR)
    .

    And 30-130min of muscle strengthening training per week can reduce the overall cancer risk (RR < 1.
    00)
    .

    In addition, 3 studies examined the association of muscle-strengthening and aerobic exercise with overall cancer mortality risk
    .

    It was found that combining muscle-strengthening training with aerobic exercise reduced the overall risk of cancer death by 28% (RR=0.
    72; 95%CI 0.
    53-0.
    98; I2=84.
    8%)
    .

    Notably, this study rated the level of evidence for overall tumor risk associated with muscle movement as 'very low'
    .

    Small driver cough, although the level of evidence is relatively low, and the effect of muscle strengthening exercise on overall cancer risk is not clear
    .

    But lack of exercise does increase cancer risk! The 2020 guideline published by Divine Journal CA shows that diet and activity may be associated with the risk of developing certain types of cancer! Table 1 Epidemiological evidence that certain diets and activities are associated with the risk of certain types of cancer [3] How can we exercise effectively? See what the guide recommends! The 2020 WHO Guidelines on Exercise and Sedentary Behavior [4] propose that exercise can bring health benefits to adults with the following chronic diseases: including stable cancer, hypertension, type 2 diabetes and HIV infection
    .

    So, how exactly do cancer patients exercise? The American College of Sports Medicine (ACSM) guidelines prescribe it
    .

    First of all, we need to evaluate the previous exercise of tumor patients, and investigate the frequency, intensity, type and time of exercise of the patient currently or in the past month [5]
    .

    If you meet the requirements of the American College of Sports Medicine (ACSM) guidelines and apply a modified exercise prescription, with a frequency of 5 times a week, a variety of exercise methods of moderate intensity or high intensity, each exercise for 20-60 minutes; if you do not meet the requirements of the ACSM guidelines , then choose the initial exercise prescription, that is, with moderate-intensity brisk walking, exercise 3 times a week, 20min/time, after 2-3 weeks, if you get used to it, use advanced exercise prescriptions, with moderate-intensity fast walking Walking mode, exercise 5 times a week, 30min/time, if you are not used to it, continue to perform the initial exercise outside
    .

    Then, if you are adapted, you can carry out a resistance training (RET) exercise prescription.
    At the intensity of 12-15RM, do 2 groups, 2 times/week, 20min/time, or you can choose an improved exercise prescription.
    Order Exercise Prescribing Cancer Treatment
    .

    It is recommended that patients receiving chemotherapy or radiotherapy should not participate in exercise training if their white blood cell count is lower than 0.
    5x109, their body temperature is higher than 38°C, and they use a wheelchair; if bone metastases occur, they should avoid heavy weight-bearing RET; if infection occurs, they should stop training , until the patient has no symptoms of infection for a whole day and then gradually resume training
    .

    How to exercise in the face of different symptoms caused by tumor? [6] Anxiety: Moderate-intensity aerobic training 3 times a week for 12 weeks, or a combination of aerobic and resistance training twice a week for 6-12 weeks, can significantly relieve cancer survivors during and after treatment anxiety
    .

    There is good evidence that resistance training alone does not relieve anxiety
    .

    Depression: Moderate-intensity aerobic training 3 times per week for at least 12 weeks, or combined aerobic and resistance training twice per week for 6 to 12 weeks, significantly reduced depression symptoms in cancer survivors during and after treatment
    .

    Fatigue: Moderate-intensity aerobic training 3 times per week for at least 12 weeks significantly reduced cancer-related fatigue during and after treatment
    .

    Combining moderate-intensity aerobic and resistance training 2-3 times per week or moderate-intensity resistance training 2 times per week is also effective, the latter being especially effective for prostate cancer
    .

    Quality of life: Combined moderate-intensity aerobic and resistance training 2-3 times per week for at least 12 weeks can improve health-related quality of life during and after treatment
    .

    Combined training is more effective than cardio or resistance training alone
    .

    Lymphedema: Past clinical recommendations have been to avoid aerobic or resistance training to avoid onset or exacerbation of lymphedema
    .

    The guide points out that for resistance training, under the supervision and guidance of professional fitness trainers, it is safe to follow the principle of "low starting point and slow progress", focusing on large muscle groups and gradually training 2 to 3 times a week
    .

    For aerobic training, the current evidence is inconclusive, but it is generally safe and did not significantly increase lymphedema-related events in the study
    .

    However, based on preliminary evidence, the above effects are only applicable to upper extremity lymphedema in breast cancer and cannot be transferred to other conditions
    .

    Physical performance: Moderate-intensity aerobic training, resistance training, or a combination of aerobic and resistance training 3 times per week for 8 to 12 weeks can significantly improve self-reported physical performance
    .

    gov/30418471/ Source: Medical Tumor Channel The 2022 CSCO Academic Annual Meeting, which is exclusively co-organized by the medical community - the Heathco Foundation's 2nd "One Hundred' Cases" Large-scale Case Collection Event is here! 25 "direct" 2022 CSCO annual meeting places to scan the code to sign up, you may be the one who will be on the stage!
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